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Tocris Bioscience™ Mandi
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Catalog No. 768110
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Quantity:
10 mg
This item is not returnable. View return policy
This item is not returnable. View return policy

Description

Highly efficient chemical inducer of proximity (CIP)

Mandi is a chemical inducer of proximity (CIP) in vivo and in vitro (EC50 = 0.43 μM in a luciferase gene expression assay). Mandi induces complex formation between PYR1Mandi, a mutant of Abscisic Acid (Cat. No. 6554) receptor PYR1, and Abscisic Acid insensitive (ABI). Mandi may be used to induce protein colocalization and interaction. It is non-toxic, orthogonal to mammalian processes and other CIPs, and highly cell permeable.

Specifications

Chemical Name or Material 4-Chloro-N-[2-[3-methoxy-4-(2-propyn-1-yloxy)phenyl]ethyl]-α-(2-propyn-1-yloxy)benzeneacetamide
CAS 374726-62-2
Quantity 10 mg
Target Protein Dimerizers
Molecular Formula C23H22ClNO4
Purity 0.98
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