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Invitrogen™ MANEA Polyclonal Antibody
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Catalog No. PIPA552781
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100 μL
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PIPA552781 100 μL
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Catalog No. PIPA552781 Supplier Invitrogen™ Supplier No. PA552781
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Description

Rabbit Polyclonal Antibody

Immunogen sequence: LRPNTATFGA PFGLDLLPEL HQRTIHLGKN FDFQKSDRIN SETNTKNLKS VEITMKPSKA SELNLDELPP LNNYLHVFYY SWYGNPQFDG KYIHWNHPVL EHWDPRIAKN YPQGRHNPPD DIGSSFYPEL GSYSSRD Highest antigen sequence identity to the following orthologs: Mouse - 79%, Rat - 76%.

N-glycosylation of proteins is initiated in the endoplasmic reticulum (ER) by the transfer of the preassembled oligosaccharide glucose-3-mannose-9-N-acetylglucosamine-2 from dolichyl pyrophosphate to acceptor sites on the target protein by an oligosaccharyltransferase complex. This core oligosaccharide is sequentially processed by several ER glycosidases and by an endomannosidase (E.C. 3.2.1.130), such as MANEA, in the Golgi. MANEA catalyzes the release of mono-, di-, and triglucosylmannose oligosaccharides by cleaving the alpha-1,2-mannosidic bond that links them to high-mannose glycans (Hamilton et al., 2005).
TRUSTED_SUSTAINABILITY

Specifications

Antigen MANEA
Applications Immunohistochemistry (Paraffin), Immunocytochemistry
Classification Polyclonal
Concentration 0.05 mg/mL
Conjugate Unconjugated
Formulation PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
Gene MANEA
Gene Accession No. Q5SRI9
Gene Alias 4932703L02Rik; alpha 1,2-endomannosidase; ENDO; Endo-alpha mannosidase; endomannosidase; glycoprotein endo-alpha-1,2-mannosidase; hEndo; Mandaselin; Manea; mannosidase endo-alpha; mannosidase, endo-alpha; mEndo
Gene Symbols MANEA
Host Species Rabbit
Immunogen Recombinant protein corresponding to Human MANEA. Recombinant protein control fragment (Product #RP-90479).
Purification Method Antigen affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 79694
Target Species Human
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG
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