Invitrogen™ MAP1LC3B2 Polyclonal Antibody

Catalog No.	Quantity
FEPA5144237	100 μg

Catalog No. FEPA5144237 Supplier Invitrogen™ Supplier No. PA5144237

Description

Rabbit Polyclonal Antibody

MAP1LC3B2 Polyclonal Antibody for ICC/IF, ELISA

Ubiquitin-like modifier involved in formation of autophagosomal vacuoles (autophagosomes). Plays a role in mitophagy which contributes to regulate mitochondrial quantity and quality by eliminating the mitochondria to a basal level to fulfill cellular energy requirements and preventing excess ROS production. In response to cellular stress and upon mitochondria fission, binds C-18 ceramides and anchors autophagolysosomes to outer mitochondrial membranes to eliminate damaged mitochondria. While LC3s are involved in elongation of the phagophore membrane, the GABARAP/GATE-16 subfamily is essential for a later stage in autophagosome maturation.

Specifications

• Antigen: MAP1LC3B2
• Applications: ELISA, Immunocytochemistry
• Classification: Polyclonal
• Concentration: 3 mg/mL
• Conjugate: Unconjugated
• Formulation: PBS with 50% glycerol and 0.03% Proclin 300; pH 7.4
• Gene: MAP1LC3B2
• Gene Accession No.: A6NCE7
• Gene Alias: ATG8G; MAP1LC3B2; Microtubule associated protein 1 light chain 3 beta 2; Microtubule associated proteins 1A/1B light chain 3B like protein; Microtubule-associated proteins 1A/1B light chain 3 beta 2; Microtubule-associated proteins 1A/1B light chain 3B-like; MP3B2_HUMAN
• Gene Symbols: MAP1LC3B2
• Host Species: Rabbit
• Immunogen: Recombinant Human Microtubule-associated proteins 1A/1B light chain 3 beta 2 protein (1-47AA).
• Purification Method: Protein G
• Quantity: 100 μg
• Regulatory Status: RUO
• Primary or Secondary: Primary
• Gene ID (Entrez): 643246
• Target Species: Human
• Content And Storage: -20°C or -80°C if preferred
• Product Type: Antibody
• Form: Liquid
• Isotype: IgG