Invitrogen™ MAP2 Polyclonal Antibody

Chicken Polyclonal Antibody

Supplier:  Invitrogen™ PA116751

Catalog No. APPA6751

Description

In Western blot bands can be seen at approximately 280 kDa, representing MAP2a and MAP2b. Bands may also be seen at approximately 70 kDa, representing MAP2c.

MAP2 (Microtubule Associated Protein 2) exists in two high molecular weight forms (MAP2a & MAP2b) and a low molecular weight form. The expression of MAP2 is developmentally regulated and its multiple forms arise by alternative splicing of a single gene. MAP2 is involved in microtubule assembly, which is an essential step in neurogenesis. The products of similar genes in rat and mouse are neuron-specific cytoskeletal proteins that are enriched in dendrites, implicating a role in determining and stabilizing dendritic shape during neuron development. MAP2 is useful in studies of neuron structure in normal and malignant brain tissue as well as in degenerative diseases such as Alzheimer's Disease (AD).

Specifications

• Antigen: MAP2
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: Map2
• Gene Alias: a730034c02; AC091465.1; DKFZp686I2148; G1-397-34; MAP 2; Map2; MAP-2; map2.S; map2a; map-2a; map2ab; MAP2B; MAP2C; MAP2R; microtubule associated protein 2; microtubule associated protein 2 S homeolog; microtubule associated protein 2; microtubule-associated protein 2; microtubule associated protein 2C; microtubule-associated protein 2; microtubule-associated protein-2; Mtap2; Mtap-2; OTTHUMP00000163916; OTTHUMP00000208143; repro4; XELAEV_18047318mg; xmap2
• Host Species: Chicken
• Purification Method: IgY Fraction
• Regulatory Status: RUO
• Gene ID (Entrez): 17756, 25595, 4133
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid

• Applications: Immunohistochemistry (Frozen), Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry
• Concentration: Conc. Not Determined
• Formulation: PBS with 0.035% sodium azide
• Gene Accession No.: P11137, P15146, P20357
• Gene Symbols: Map2
• Immunogen: Recombinant human construct of projection domain sequences, amino acds 377-1505.
• Quantity: 50 μL
• Primary or Secondary: Primary
• Target Species: Human, Mouse, Rat
• Product Type: Antibody
• Isotype: IgY