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MAP2K2 Monoclonal Antibody (OTI5G8), TrueMAB™, OriGene
SDP

Mouse Monoclonal Antibody

Supplier:  OriGene TA505716

Encompass_Preferred

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Catalog No. 50-167-6153


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Description

Description

MEK1 (Mitogen activated protein kinase kinase 1) catalyzes the concomitant phosphorylation of a threonine and a tyrosine residue in a Thr-Glu-Tyr sequence located in MAP kinases. MEK1 activates ERK1 and ERK2 MAP kinases. Mitogen activated protein kinase kinase 2 (MEK2 or MAPKK2) is a member of a family of tyrosine/threonine protein kinases that activate the ERK1 and 2 and MAPK enzymes by phosphorylating both residues within the threonine/glutamate/tyrosine (TEY) motif in the activation loop. MEK1 and 2 are also activated by dual phosphorylation, which occurs on serine 218 and 222, in the activation loop of the MEK. Threonine 292 of MEK1 is phosphorylated by ERK 2, which serves as a negative feedback loop by suppressing activation of MEK1.
Specifications

Specifications

MAP2K2
Monoclonal
1 mg/mL
PBS with 1% BSA, 50% glycerol and 0.02% sodium azide
P36506, P36507, Q63932
MAP2K2
Full length human recombit protein of human MAP2K2 produced in HEK293T cell.
100 μL
Primary
Canine, Human, Mouse, Rat
Antibody
IgG2a
Immunocytochemistry, Immunofluorescence, Western Blot
OTI5G8
Unconjugated
MAP2K2
CFC4, MAPKK2, MEK2, MKK2, PRKMK2
Mouse
Affinity Chromatography
RUO
26396, 5605, 58960, 611939
-20° C, Avoid Freeze/Thaw Cycles
Liquid
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