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MAP3K1 Rabbit anti-Human, Mouse, Rat, Polyclonal, Proteintech
SDP

Rabbit Polyclonal Antibody

Supplier:  Proteintech Group Inc 199701AP150UL

Encompass_Preferred

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Catalog No. 50-109-2806


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Description

Description

The antibody recognizes the N-term of MAP3K1.

Mitogen-activated protein kinase (MAPK) signaling cascades include MAPK or extracellular signal-regulated kinase (ERK), MAPK kinase (MKK or MEK), and MAPK kinase kinase (MAPKKK or MEKK). MAPKK kinase/MEKK phosphorylates and activates its downstream protein kinase, MAPK kinase/MEK, which in turn activates MAPK. The kinases of these signaling cascades are highly conserved, and homologs exist in yeast, Drosophila, and mammalian cells. MEKK1 can phosphorylate and activate MAPKK 1 and MAPKK 2 (MEK1/MEK2) which leads to phosphorylation of MAP kinases. It is also a highly efficient activator of the JNK cascade. The protein contains a putative 1 RING-type zinc finger and 1 SWIM-type zinc finger.
Specifications

Specifications

MAP3K1
Polyclonal
Unconjugated
MAP3K1
MAP3K1, MAPK/ERK kinase kinase 1, MAPKKK1, MEK kinase 1, MEKK, MEKK 1, MEKK1
Rabbit
Antigen Affinity Chromatography
RUO
116667, 26401, 4214
-20°C
Liquid
Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot
0.41 mg/mL
PBS with 50% glycerol and 0.1% sodium azide; pH 7.3
P53349, Q13233, Q62925
MAP3K1
Peptide
150 μL
Primary
Human, Mouse, Rat
Antibody
IgG
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