Invitrogen™ MAP4 Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA596473

Catalog No. PIPA596473

Description

Immunogen sequence: TENIKHQPGG GRAKVEKKTE AAATTRKPES NAVTKTAGPI ASAQKQPAGK VQIVSKKVSY SHIQSKCGSK DNIKHVPGGG NVQIQNKKVD ISKVSSKCGS KANIKHKPGG GDVKIESQKL NFKEKAQAKV GSLDNVGHLP AGGAVKTEGG GSEAPLCPGP PAGEEPAISE AAPEAGAPTS ASGLNGHPTL SGGGDQREAQ TLDSQIQETS I; Positive Samples: U-87MG; Cellular Location: Cytoplasm, cytoskeleton.

The protein encoded by this gene is a major non-neuronal microtubule-associated protein. This protein contains a domain similar to the microtubule-binding domains of neuronal microtubule-associated protein (MAP2) and microtubule-associated protein tau (MAPT/TAU). This protein promotes microtubule assembly, and has been shown to counteract destabilization of interphase microtubule catastrophe promotion. Cyclin B was found to interact with this protein, which targets cell division cycle 2 (CDC2) kinase to microtubules. The phosphorylation of this protein affects microtubule properties and cell cycle progression. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq].

Specifications

• Antigen: MAP4
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: MAP4
• Gene Alias: AA407148; MAP 4; Map4; MAP-4; microtubule associated protein 4; microtubule-associated protein 4; Mtap4; Mtap-4
• Host Species: Rabbit
• Purification Method: Affinity Chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 17758, 4134
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
• Form: Liquid

• Applications: ELISA, Immunohistochemistry (Paraffin), Western Blot
• Concentration: 2.09 mg/mL
• Formulation: PBS with 50% glycerol and 0.01% thimerosal; pH 7.3
• Gene Accession No.: P27546, P27816
• Gene Symbols: MAP4
• Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 942-1152 of human MAP4 (NP_0023662).
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human, Mouse
• Product Type: Antibody
• Isotype: IgG