Invitrogen™ MAP4K2 Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA5116226

Catalog No. PIPA5116226

Description

MAP4K2 Polyclonal Antibody for Western Blot

MAP4K2 (GCK) is a serine/ threonine protein kinase that activates the JNK pathway. Although this kinase is found in many tissues, its expression in lymphoid follicles is restricted to the cells of the germinal center, where it may participate in B-cell differentiation. The kinase may also play a role in the regulation of vesicle targeting or fusion. The protein encoded by MAP4K2 is a member of the serine/threonine protein kinase family. Although this kinase is found in many tissues, its expression in lymphoid follicles is restricted to the cells of germinal centre, where it may participate in B-cell differentiation. This kinase can be activated by TNF-alpha, and has been shown to specifically activate MAP kinases. This kinase is also found to interact with TNF receptor-associated factor 2 (TRAF2), which is involved in the activation of MAP3K1/MEKK1.

Specifications

• Antigen: MAP4K2
• Classification: Polyclonal
• Formulation: PBS with 0.09% sodium azide; pH 7.4
• Gene Accession No.: Q61161
• Gene Symbols: MAP4K2
• Immunogen: KLH conjugated synthetic peptide between 432-459 amino acids from the Central region of mouse Map4k2.
• Quantity: 400 μL
• Primary or Secondary: Primary
• Target Species: Mouse
• Product Type: Antibody
• Isotype: IgG

• Applications: Western Blot
• Conjugate: Unconjugated
• Gene: MAP4K2
• Gene Alias: AI385662; B lymphocyte serine/threonine protein kinase; B lymphocyte serine/threonine-protein kinase; BL44; dZ150L22.2; GC kinase; GCK; germinal center kinase; germinal centre kinase (GC kinase); LOW QUALITY PROTEIN: mitogen-activated protein kinase kinase kinase kinase 2; MAP4K2; map4k2l; map4k2l-2; map4k3l; MAPK/ERK kinase kinase kinase 2; MEK kinase kinase 2; MEKKK 2; mitogen activated protein kinase kinase kinase kinase 2; mitogen-activated protein kinase kinase kinase kinase 2; mitogen-activated protein kinase kinase kinase kinase 2-like; mitogen-activated protein kinase kinase kinase kinase 3-like; Rab8 interacting protein; rab8-interacting protein; Rab8ip; si:dz150l22.2; si:dz263j20.1; Unknown (protein for MGC:136670); zgc:136670
• Host Species: Rabbit
• Purification Method: Antigen Affinity Chromatography, Protein A
• Regulatory Status: RUO
• Gene ID (Entrez): 26412
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid

Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov