MAP4K3 Mouse anti-Human, Clone: 219CT8.3.1, Abnova™
Mouse monoclonal antibody raised against human MAP4K3.
Manufacturer: Abnova Corporation MAB12312
This gene encodes a member of the Ste20 family of serine/threonine protein kinases. The protein belongs to the subfamily that consists of members, such as germinal center kinase (GCK), that are characterized by an N-terminal catalytic domain and C-terminal regulatory domain. The kinase activity of the encoded protein can be stimulated by UV radiation and tumor necrosis factor-alpha. The protein specifically activates the c-Jun N-terminal kinase (JNK) signaling pathway. Evidence suggests that it functions upstream of mitogen-activated protein kinase kinase kinase 1 (MEKK1). This gene previously was referred to as RAB8-interacting protein-like 1 (RAB8IPL1), but it has been renamed mitogen-activated protein kinase kinase kinase kinase 3 (MAP4K3). [provided by RefSeq]
|Mouse monoclonal antibody raised against human MAP4K3.|
|In PBS (0.09% sodium azide)|
|Store at 4°C. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.
|Immunohistochemistry (PFA fixed), Western Blot|
|Immunohistochemistry (1:100) Western Blot (1:100-1:500) The optimal working dilution should be determined by the end user.|
|Recombinant protein corresponding to human MAP4K3.|
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