MAP4K4/HGK Polyclonal Antibody, Bethyl Laboratories

Rabbit Polyclonal Antibody

Supplier:  Bethyl Laboratories, Inc A301503AT

Catalog No. 50-156-0559

Description

The recommended shelf life for this product is 1 year from date of receipt. Based on 100% sequence identity, this antibody is predicted to react with Mouse

M4K4, a member of the STE20 subfamily of Ser/Thr protein kinases, may play a role in the response to environmental stress and cytokines such as TNF-alpha. It appears to act upstream of the JUN N-terminal pathway. This protein is thought to interact with the SH3 domain of the adapter proteins Nck. HGK binds, via its CNH regulatory domain, to the N-terminal region of SPG3A. Expression appears to be ubiquitous, expressed in all tissue types examined. Isoform 5 appears to be more abundant in the brain, and isoform 4 is predomit in the liver, skeletal muscle and placenta.

Specifications

• Antigen: MAP4K4/HGK
• Classification: Polyclonal
• Formulation: TBS with 0.1% BSA and 0.09% sodium azide
• Gene Accession No.: O95819
• Gene Symbols: MAP4K4
• Immunogen: Between 850 and 900
• Quantity: 20 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG

• Applications: Western Blot
• Conjugate: Unconjugated
• Gene: MAP4K4
• Gene Alias: Mitogen-activated protein kinase kinase kinase kinase 4; MAPK/ERK kinase kinase kinase 4; MEK kinase kinase 4; HPK/GCK-like kinase HGK; Nck interacting kinase; MEKKK 4; MAP4K4; NIK; KIAA0687
• Host Species: Rabbit
• Purification Method: Antigen affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 9448
• Content And Storage: 4° C
• Form: Liquid