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Invitrogen™ MAPK15 Monoclonal Antibody (168CT10.6.6)
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Catalog No. PIMA537481
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400 μL
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Catalog No. Quantity
PIMA537481 400 μL
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Catalog No. PIMA537481 Supplier Invitrogen™ Supplier No. MA537481
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Description

Mouse Monoclonal Antibody

MAPK15 Monoclonal Antibody for Western Blot, ICC/IF

The ERKs are a subfamily of the MAPKs that have been implicated in cell growth and differentiation. Extracellular signal-regulated kinase 8 (Erk8) is a large MAP kinase whose activity is controlled by serum and the c-Src non-receptor tyrosine kinase. ERK8 down-regulates transactivation of the glucocorticoid receptor through Hic-5 and can negatively regulate transcriptional co-activation of androgen receptor and GRalpha by Hic-5 in a kinase-independent manner, suggesting a broader role for ERK8 in the regulation of nuclear receptors beyond estrogen receptor alpha. Erk8 is a novel effector of RET/PTC3 and, therefore, RET biological functions.
TRUSTED_SUSTAINABILITY

Specifications

Antigen MAPK15
Applications Western Blot, Immunocytochemistry
Classification Monoclonal
Clone 168CT10.6.6
Conjugate Unconjugated
Formulation PBS with 0.09% sodium azide; pH 7.4
Gene MAPK15
Gene Accession No. Q8TD08
Gene Alias BC048082; EC 2.7.11.24; ERK7; ERK-7; ERK8; ERK-8; extracellular regulated kinase 8 delta; extracellular signal regulated kinase 8; extracellular signal-regulated kinase 7; Extracellular signal-regulated kinase 8; MAP kinase 15; MAPK 15; Mapk15; Mitogen-activated protein kinase 15
Gene Symbols MAPK15
Host Species Mouse
Immunogen MAPK15 recombinant protein.
Purification Method Protein G
Quantity 400 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 225689
Target Species Human
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG1 κ
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Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov
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