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MAPK15 Mouse anti-Human, Clone: 8C6, Bioss
SDP

Catalog No. 501979805
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100 μL
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50-197-9805 100 μL
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Catalog No. 50-197-9805 Supplier Bioss Supplier No. BSM51037M
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Description

Mouse Monoclonal Antibody

The ERKs are a subfamily of the MAPKs that have been implicated in cell growth and differentiation. Extracellular signal-regulated kinase 8 (Erk8) is a large MAP kinase whose activity is controlled by serum and the c-Src non-receptor tyrosine kinase. ERK8 down-regulates transactivation of the glucocorticoid receptor through Hic-5 and can negatively regulate transcriptional co-activation of androgen receptor and GRalpha by Hic-5 in a kinase-independent manner, suggesting a broader role for ERK8 in the regulation of nuclear receptors beyond estrogen receptor alpha. Erk8 is a novel effector of RET/PTC3 and, therefore, RET biological functions.

Specifications

Antigen MAPK15
Applications Immunofluorescence, Western Blot
Classification Monoclonal
Clone 8C6
Concentration 1 μg/mL
Conjugate Unconjugated
Formulation TBS with 1% BSA, 40% glycerol and 0.05% sodium azide; pH
Gene MAPK15
Gene Accession No. Q8TD08
Gene Alias BC048082; EC 2.7.11.24; Erk7; ERK-7; ERK8; ERK-8; extracellular regulated kinase 8 delta; extracellular signal regulated kinase 8; Extracellular signal-regulated kinase 7; Extracellular signal-regulated kinase 8; MAP kinase 15; MAPK 15; Mapk15; Mitogen-activated protein kinase 15
Gene Symbols MAPK15
Host Species Mouse
Immunogen This MAPK15 monoclonal antibody is generated from mouse immunized with MAPK15 recombinant protein.
Purification Method Protein G
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 225689
Target Species Human
Content And Storage -20°C
Product Type Antibody
Form Liquid
Isotype IgG1 κ
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