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Invitrogen™ MAPKAPK3 Monoclonal Antibody (01)
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Catalog No. PIMA529410
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100 μL
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PIMA529410 100 μL
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Catalog No. PIMA529410 Supplier Invitrogen™ Supplier No. MA529410
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Description

Mouse Monoclonal Antibody

This product is preservative free. It is recommended to add sodium azide to avoid contamination (final concentration 0.05%-0.1%). This antibody has specificity for Human MAPKAPK3/MK3.

MAPKAPK3 functions as an integrative element of signaling in both mitogen and stress responses. MAPKAPK3 functions as a mitogen-activated protein kinase (MAP kinase)- activated protein kinase. MAP kinases are also known as extracellular signal-regulated kinases (ERKs), act as an integration point for multiple biochemical signals. MAPKAPK3 was shown to be activated by growth inducers and stress stimulation of cells. In vitro studies demonstrated that ERK, p38 MAP kinase and Jun N-terminal kinase were all able to phosphorylate and activate this kinase, which suggested the role of this kinase as an integrative element of signaling in both mitogen and stress responses. MAPKAPK3 was reported to interact with, phosphorylate and repress the activity of E47, which is a basic helix-loop-helix transcription factor known to be involved in the regulation of tissue-specific gene expression and cell differentiation.
TRUSTED_SUSTAINABILITY

Specifications

Antigen MAPKAPK3
Applications Immunohistochemistry (Paraffin)
Classification Monoclonal
Clone 01
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with no preservative
Gene MAPKAPK3
Gene Accession No. Q16644
Gene Alias 3PK; AI874665; chromosome 3p kinase; MAP kinase-activated protein kinase 3; MAPK-activated protein kinase 3; MAPKAP kinase 3; MAPKAP3; MAPKAPK3; MAPKAP-K3; MAPKAPK-3; MapkKapk3; mitogen activated protein kinase-activated protein kinase 3; mitogen-activated protein kinase-activated protein kinase 3; MK3; MK-3; OTTHUMP00000210806; OTTHUMP00000210807
Gene Symbols MAPKAPK3
Host Species Mouse
Immunogen Recombinant Human MAPKAPK3/MK3 Protein (Met1-Gln382).
Purification Method Protein A
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 7867
Target Species Human
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG2a
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