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Invitrogen™ MAPKAPK3 Polyclonal Antibody
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Catalog No. PIPA5115542
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100 μL
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PIPA5115542 100 μL
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Catalog No. PIPA5115542 Supplier Invitrogen™ Supplier No. PA5115542
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Description

Rabbit Polyclonal Antibody

Antibody detects endogenous levels of total MAPK3.

MAPKAPK3 functions as an integrative element of signaling in both mitogen and stress responses. MAPKAPK3 functions as a mitogen-activated protein kinase (MAP kinase)- activated protein kinase. MAP kinases are also known as extracellular signal-regulated kinases (ERKs), act as an integration point for multiple biochemical signals. MAPKAPK3 was shown to be activated by growth inducers and stress stimulation of cells. In vitro studies demonstrated that ERK, p38 MAP kinase and Jun N-terminal kinase were all able to phosphorylate and activate this kinase, which suggested the role of this kinase as an integrative element of signaling in both mitogen and stress responses. MAPKAPK3 was reported to interact with, phosphorylate and repress the activity of E47, which is a basic helix-loop-helix transcription factor known to be involved in the regulation of tissue-specific gene expression and cell differentiation.
TRUSTED_SUSTAINABILITY

Specifications

Antigen MAPKAPK3
Applications Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry
Classification Polyclonal
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.02% sodium azide
Gene MAPKAPK3
Gene Accession No. Q16644, Q3UMW7, Q66H84
Gene Alias 3PK; AI874665; chromosome 3p kinase; MAP kinase-activated protein kinase 3; MAPK-activated protein kinase 3; MAPKAP kinase 3; MAPKAP3; MAPKAPK3; MAPKAP-K3; MAPKAPK-3; MapkKapk3; mitogen activated protein kinase-activated protein kinase 3; mitogen-activated protein kinase-activated protein kinase 3; MK3; MK-3; OTTHUMP00000210806; OTTHUMP00000210807
Gene Symbols MAPKAPK3
Host Species Rabbit
Immunogen A synthesized peptide derived from human MAPKAPK3(Accession Q16644), corresponding to amino acid residues M299-V349.
Purification Method Affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 102626, 315994, 7867
Target Species Human, Mouse, Rat
Content And Storage -20°C
Product Type Antibody
Form Liquid
Isotype IgG
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