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Invitrogen™ MAPKAPK5 Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA599329

Catalog No. PIPA599329


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Description

Description

Antibody detects endogenous levels of total MAPKAPK5.

MAPKAPK5 (PRAK) is activated in response to cellular stress and pro-inflammatory cytokines. Activity of this kinase is regulated by p38 alpha and p38 beta. The protein encoded by PRAK is a member of the serine/threonine kinase family. In response to cellular stress and proinflammatory cytokines, this kinase is activated through its phosphorylation by MAP kinases including MAPK1/ERK, MAPK14/p38-alpha, and MAPK11/p38-beta. In vitro, this kinase phosphorylates heat shock protein HSP27 at its physiologically relevant sites. Two alternately spliced transcript variants of PRAK encoding distinct isoforms have been reported.
TRUSTED_SUSTAINABILITY
Specifications

Specifications

MAPKAPK5
Polyclonal
Unconjugated
MAPKAPK5
MAP kinase-activated protein kinase 5; MAPK-activated protein kinase 5; MAPKAP kinase 5; Mapkapk5; MAPKAP-K5; MAPKAPK-5; mitogen-activated protein kinase-activated protein kinase 5; MK5; MK-5; p38-regulated/activated protein kinase; PRAK
Rabbit
Affinity chromatography
RUO
17165, 8550
-20°C
Liquid
Western Blot, Immunocytochemistry
1 mg/mL
PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
O54992, Q8IW41
MAPKAPK5
A synthesized peptide derived from human MAPKAPK5(Accession Q8IW41), corresponding to amino acid residues G328-D378.
100 μL
Primary
Human, Mouse
Antibody
IgG
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