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Invitrogen™ MAPKAPK5 Polyclonal Antibody
Rabbit Polyclonal Antibody
Supplier: Invitrogen™ PA599329
Description
Antibody detects endogenous levels of total MAPKAPK5.
MAPKAPK5 (PRAK) is activated in response to cellular stress and pro-inflammatory cytokines. Activity of this kinase is regulated by p38 alpha and p38 beta. The protein encoded by PRAK is a member of the serine/threonine kinase family. In response to cellular stress and proinflammatory cytokines, this kinase is activated through its phosphorylation by MAP kinases including MAPK1/ERK, MAPK14/p38-alpha, and MAPK11/p38-beta. In vitro, this kinase phosphorylates heat shock protein HSP27 at its physiologically relevant sites. Two alternately spliced transcript variants of PRAK encoding distinct isoforms have been reported.
Specifications
MAPKAPK5 | |
Polyclonal | |
Unconjugated | |
MAPKAPK5 | |
MAP kinase-activated protein kinase 5; MAPK-activated protein kinase 5; MAPKAP kinase 5; Mapkapk5; MAPKAP-K5; MAPKAPK-5; mitogen-activated protein kinase-activated protein kinase 5; MK5; MK-5; p38-regulated/activated protein kinase; PRAK | |
Rabbit | |
Affinity chromatography | |
RUO | |
17165, 8550 | |
-20°C | |
Liquid |
Western Blot, Immunocytochemistry | |
1 mg/mL | |
PBS with 50% glycerol and 0.02% sodium azide; pH 7.4 | |
O54992, Q8IW41 | |
MAPKAPK5 | |
A synthesized peptide derived from human MAPKAPK5(Accession Q8IW41), corresponding to amino acid residues G328-D378. | |
100 μL | |
Primary | |
Human, Mouse | |
Antibody | |
IgG |
Safety and Handling
WARNING: Cancer - www.P65Warnings.ca.gov
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