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Invitrogen™ MARCH1 Polyclonal Antibody
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Catalog No. PIPA5103815
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100 μL
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PIPA5103815 100 μL
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Catalog No. PIPA5103815 Supplier Invitrogen™ Supplier No. PA5103815
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Description

Rabbit Polyclonal Antibody

Antibody detects endogenous levels of total MARCH1.

E3 ubiquitin-protein ligase that mediates ubiquitination of TFRC, CD86, FAS and MHC class II proteins, such as HLA-DR alpha and beta, and promotes their subsequent endocytosis and sorting to lysosomes via multivesicular bodies. By constitutively ubiquitinating MHC class II proteins in immature dendritic cells, down-regulates their cell surface localization thus sequestering them in the intracellular endosomal system.
TRUSTED_SUSTAINABILITY

Specifications

Antigen MARCH1
Applications Western Blot, Immunocytochemistry
Classification Polyclonal
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
Gene MARCH1
Gene Accession No. Q6NZQ8, Q8TCQ1
Gene Alias 1-Mar; 2900024D24Rik; BB085186; E3 ubiquitin-protein ligase MARCH1; MARCH1; MARCHF1; MARCH-I; membrane associated ring finger 1; membrane associated ring-CH-type finger 1; membrane-associated ring finger (C3HC4) 1; membrane-associated ring finger (C3HC4) 1, E3 ubiquitin protein ligase; membrane-associated RING finger protein 1; Membrane-associated RING-CH protein I; RGD1305148; RING finger protein 171; RING-type E3 ubiquitin transferase MARCH1; RNF171
Gene Symbols MARCH1
Host Species Rabbit
Immunogen A synthesized peptide derived from human MARCH1(Accession Q8TCQ1), corresponding to amino acid residues V223-A273.
Purification Method Affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 361135, 55016, 72925
Target Species Human, Mouse, Rat
Content And Storage -20°C
Product Type Antibody
Form Liquid
Isotype IgG
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Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov
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