Invitrogen™ MARCH2 Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA569220

Catalog No. PIPA569220

Description

This target displays homology in the following species: Cow: 93%; Dog: 100%; Guinea Pig: 100%; Horse: 100%; Human: 100%; Mouse: 100%; Rabbit: 100%; Rat: 100%.

MARCH2 is a member of the MARCH family of membrane-bound E3 ubiquitin ligases (EC 6.3.2.19). MARCH enzymes add ubiquitin (see MIM 191339) to target lysines in substrate proteins, thereby signaling their vesicular transport between membrane compartments. MARCH2 reduces surface accumulation of several glycoproteins and appears to regulate early endosome-to-trans-Golgi network (TGN) trafficking (Bartee et al., 2004 [PubMed 14722266]; Nakamura et al., 2005 [PubMed 15689499]).

Specifications

• Antigen: MARCH2
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: MARCHF2
• Gene Alias: 9530046H09Rik; E3 ubiquitin-protein ligase MARCH2; HSPC240; MARCH2; MARCHF2; MARCH-II; membrane associated ring finger 2; membrane associated RING-CH finger protein II; membrane associated ring-CH-type finger 2; membrane-associated ring finger (C3HC4) 2; membrane-associated ring finger (C3HC4) 2, E3 ubiquitin protein ligase; membrane-associated RING finger protein 2; Membrane-associated RING-CH protein II; RGD1306395; RING finger protein 172; RING-type E3 ubiquitin transferase MARCH2; RNF172; syntaxin-6-binding protein
• Host Species: Rabbit
• Purification Method: Affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 224703
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
• Form: Liquid

• Applications: Western Blot
• Concentration: 0.5 mg/mL
• Formulation: PBS with 2% sucrose and 0.09% sodium azide
• Gene Accession No.: Q99M02
• Gene Symbols: MARCHF2
• Immunogen: synthetic peptide directed towards the middle region of human MARCH2 (aa 151-200).
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Mouse
• Product Type: Antibody
• Isotype: IgG