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MARCH2 Rabbit anti-Human, Polyclonal, Bioss
SDP

Catalog No. 501988994
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100 μL
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50-198-8994 100 μL
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Catalog No. 50-198-8994 Supplier Bioss Supplier No. BS9336R
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Description

Rabbit Polyclonal Antibody

MARCH2 is a member of the MARCH family of membrane-bound E3 ubiquitin ligases (EC 6.3.2.19). MARCH enzymes add ubiquitin (see MIM 191339) to target lysines in substrate proteins, thereby signaling their vesicular transport between membrane compartments. MARCH2 reduces surface accumulation of several glycoproteins and appears to regulate early endosome-to-trans-Golgi network (TGN) trafficking (Bartee et al., 2004 [PubMed 14722266]; Nakamura et al., 2005 [PubMed 15689499]).

Specifications

Antigen MARCH2
Applications Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot
Classification Polyclonal
Concentration 1 μg/mL
Conjugate Unconjugated
Formulation PBS with 1% BSA, 50% glycerol and 0.09% sodium azide; pH
Gene Alias E3 ubiquitin-protein ligase MARCH2; March2; membrane associated ring-CH-type finger 2
Host Species Rabbit
Immunogen KLH conjugated synthetic peptide derived from human MARCH2.
Purification Method Protein A
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Target Species Human
Content And Storage -20°C
Product Type Antibody
Form Liquid
Isotype IgG
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