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Invitrogen™ MARCH4 Polyclonal Antibody
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Catalog No. PIPA5116198
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400 μL
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PIPA5116198 400 μL
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Catalog No. PIPA5116198 Supplier Invitrogen™ Supplier No. PA5116198
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Description

Rabbit Polyclonal Antibody

MARCH4 Polyclonal Antibody for Western Blot

RNF174 (MARCH4) is a multi-pass membrane protein mainly found in the membrane of Golgi apparatus. It is a complex enzyme with a RING-CH-type zinc finger. It acts as a ubiquitin-protein ligase mainly involved in third step of ubiquitin conjugation. The RINGv-type zinc finger domain is required for E3 ligase activity in which the E3 ubiquitin-protein ligase mediates ubiquitination of MHC-I and CD4, and promote their subsequent endocytosis and sorting to lysosomes via multivesicular bodies. It is mainly expressed in brain and placenta.
TRUSTED_SUSTAINABILITY

Specifications

Antigen MARCH4
Applications Western Blot
Classification Polyclonal
Concentration 0.4 mg/mL
Conjugate Unconjugated
Formulation PBS with 0.09% sodium azide; pH 7.4
Gene MARCH4
Gene Accession No. Q9P2E8
Gene Alias BC056494; E3 ubiquitin-protein ligase MARCH4; Kiaa1399; MARCH4; MARCHF4; MARCH-IV; membrane associated ring finger 4; membrane associated ring-CH-type finger 4; membrane-associated ring finger (C3HC4) 4; membrane-associated ring finger (C3HC4) 4, E3 ubiquitin protein ligase; membrane-associated RING finger protein 4; Membrane-associated RING-CH protein IV; mKIAA1399; RING finger protein 174; RING-type E3 ubiquitin transferase MARCH4; RNF174
Gene Symbols MARCH4
Host Species Rabbit
Immunogen KLH conjugated synthetic peptide between 302-331 amino acids from the C-terminal region of human MARCH4.
Purification Method Antigen affinity chromatography, Protein A
Quantity 400 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 57574
Target Species Human
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG
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Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov
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