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Invitrogen™ MARCH4 Polyclonal Antibody
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Catalog No. PIPA523146
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100 μg
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Catalog No. Quantity
PIPA523146 100 μg
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Catalog No. PIPA523146 Supplier Invitrogen™ Supplier No. PA523146
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Description

Rabbit Polyclonal Antibody

Immunogen sequence homology: Monkey (88%).

RNF174 (MARCH4) is a multi-pass membrane protein mainly found in the membrane of Golgi apparatus. It is a complex enzyme with a RING-CH-type zinc finger. It acts as a ubiquitin-protein ligase mainly involved in third step of ubiquitin conjugation. The RINGv-type zinc finger domain is required for E3 ligase activity in which the E3 ubiquitin-protein ligase mediates ubiquitination of MHC-I and CD4, and promote their subsequent endocytosis and sorting to lysosomes via multivesicular bodies. It is mainly expressed in brain and placenta.
TRUSTED_SUSTAINABILITY

Specifications

Antigen MARCH4
Applications Immunohistochemistry (Paraffin), Western Blot
Classification Polyclonal
Concentration 0.5 mg/mL
Conjugate Unconjugated
Formulation PBS with 0.2% gelatin and 0.05% sodium azide
Gene MARCH4
Gene Accession No. Q80TE3, Q9P2E8
Gene Alias BC056494; E3 ubiquitin-protein ligase MARCH4; Kiaa1399; MARCH4; MARCHF4; MARCH-IV; membrane associated ring finger 4; membrane associated ring-CH-type finger 4; membrane-associated ring finger (C3HC4) 4; membrane-associated ring finger (C3HC4) 4, E3 ubiquitin protein ligase; membrane-associated RING finger protein 4; Membrane-associated RING-CH protein IV; mKIAA1399; RING finger protein 174; RING-type E3 ubiquitin transferase MARCH4; RNF174
Gene Symbols MARCH4
Host Species Rabbit
Immunogen A portion of amino acids 300-350 of human RNF174.
Purification Method Antigen affinity chromatography
Quantity 100 μg
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 100050538, 367295, 381270, 57574
Target Species Human, Mouse, Rat, Monkey, Horse
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG
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