MARCH4 Rabbit anti-Human, Polyclonal, Bioss

Catalog No.	Quantity
50-198-8996	100 μL

Catalog No. 50-198-8996 Supplier Bioss Supplier No. BS9338R

Description

Rabbit Polyclonal Antibody

RNF174 (MARCH4) is a multi-pass membrane protein mainly found in the membrane of Golgi apparatus. It is a complex enzyme with a RING-CH-type zinc finger. It acts as a ubiquitin-protein ligase mainly involved in third step of ubiquitin conjugation. The RINGv-type zinc finger domain is required for E3 ligase activity in which the E3 ubiquitin-protein ligase mediates ubiquitination of MHC-I and CD4, and promote their subsequent endocytosis and sorting to lysosomes via multivesicular bodies. It is mainly expressed in brain and placenta.

Specifications

• Antigen: MARCH4
• Applications: Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot
• Classification: Polyclonal
• Concentration: 1 μg/mL
• Conjugate: Unconjugated
• Formulation: PBS with 1% BSA, 50% glycerol and 0.09% sodium azide; pH
• Gene: 43894
• Gene Accession No.: Q9P2E8
• Gene Alias: BC056494; E3 ubiquitin-protein ligase MARCH4; Kiaa1399; March4; MARCH-IV; membrane associated ring finger 4; membrane associated ring-CH-type finger 4; membrane-associated ring finger (C3HC4) 4; membrane-associated ring finger (C3HC4) 4, E3 ubiquitin protein ligase; Membrane-associated RING finger protein 4; Membrane-associated RING-CH protein IV; mKIAA1399; RING finger protein 174; RING-type E3 ubiquitin transferase MARCH4; RNF174
• Gene Symbols: 43894
• Host Species: Rabbit
• Immunogen: KLH conjugated synthetic peptide derived from human MARCH4.
• Purification Method: Protein A
• Quantity: 100 μL
• Regulatory Status: RUO
• Primary or Secondary: Primary
• Gene ID (Entrez): 57574
• Target Species: Human
• Content And Storage: -20°C
• Product Type: Antibody
• Form: Liquid
• Isotype: IgG