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Invitrogen™ MARCKS Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA587527

Catalog No. PIPA587527


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Description

Description

Immunogen sequence: MGAQFSKTAA KGEAAAERPG EAAVASSPSK ANGQENGHVK VNGDASPAAA ESGAKEELQA NGSAPAADKE EPAAAGSGAA SPSAAEKGEP AAAAAPEAGA; Positive Samples: Rat brain; Cellular Location: Cytoplasm, Lipid-anchor, Membrane, cytoskeleton.

MARCKS is a substrate for protein kinase C. It is localized to the plasma membrane and is an actin filament crosslinking protein. Phosphorylation by protein kinase C or binding to calcium-calmodulin inhibits its association with actin and with the plasma membrane, leading to its presence in the cytoplasm. The protein is thought to be involved in cell motility, phagocytosis, membrane trafficking and mitogenesis.
TRUSTED_SUSTAINABILITY
Specifications

Specifications

MARCKS
Polyclonal
Unconjugated
MARCKS
80K protein; 80K-L; 80K-L protein; FLJ14368; FLJ90045; KINC; Macs; MARCKS; MARCS; myristoylated alanine rich protein kinase C substrate; myristoylated alanine-rich C-kinase substrate; Myristoylated alanine-rich protein kinase C substrate; myristoylated alanine-rich protein kinase C substrate (MARCKS, 80K-L); phosphomyristin; PKCSL; PRKCSL; protein kinase C substrate 80 kDa protein; protein kinase C substrate, 80 kDa protein, light chain
Rabbit
Affinity chromatography
RUO
17118, 25603, 4082
-20°C, Avoid Freeze/Thaw Cycles
Liquid
ELISA, Western Blot, Immunocytochemistry
0.69 mg/mL
PBS with 50% glycerol and 0.01% thimerosal; pH 7.3
P26645, P29966, P30009
MARCKS
A synthetic peptide corresponding to a sequence within amino acids 1-100 of human MARCKS (NP_0023475).
100 μL
Primary
Human, Mouse, Rat
Antibody
IgG
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