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Invitrogen™ MARK Pan Polyclonal Antibody
Rabbit Polyclonal Antibody
Supplier: Invitrogen™ PA536396
Description
This antibody detects endogenous protein at a molecular weight of 80-92 kDa. Purity is >95% by SDS-PAGE.
MARK1 (MAP/microtubule affinity-regulating kinase 1) belongs to the MARK family of serine/threonine kinases. MARK family protein kinases phosphorylate microtubule-associated proteins and may play a role in cytoskeletal stability. MARK2 refers to MAP/microtubule affinity-regulating kinase 2 isoform a [Homo sapiens]. EMK (ELKL Motif Kinase) is a small family of ser/thr protein kinases involved in the control of cell polarity, microtubule stability and cancer. Several cDNA clones have been isolated that encoded two isoforms of the human ser/thr protein kinase EMK1 called MARK2. MARK3 was originally identified as a marker that was induced by treatment with DNA damaging agents, and loss of MARK3 was found with carcinogenesis in the pancreas. MARK4 contains an N terminal serine/threonine kinase domain, a central ubiquitin associated domain, and a C terminal KA1 associated kinase domain. RT PCR analysis detects upregulated expression of the gene for MARK4 in nearly all clinical hepatocellular carcinoma cells.
Specifications
MARK Pan | |
Polyclonal | |
Unconjugated | |
MARK3 | |
1600015G02Rik; 2410090P21Rik; A430080F22Rik; AW491150; B930025N23Rik; C79806; Cdc25C-associated protein kinase 1; cTAK1; C-TAK1; ELKL motif kinase 1; ELKL motif kinase 2; ELKL motif serine/threonine-protein kinase 3; ELKL motif serine-threonine protein kinase 3; Emk; EMK1; EMK-1; Emk2; EMK-2; EMK2/MARK3 serine-threonine protein kinase; Emk3; ETK1; ETK-1; KIAA1477; Kiaa1860; KP78; MAP/microtubule affinity regulating kinase 1; MAP/microtubule affinity regulating kinase 2; MAP/microtubule affinity regulating kinase 3; MAP/microtubule affinity regulating kinase 4; MAP/microtubule affinity-regulating kinase 1; MAP/microtubule affinity-regulating kinase 2; MAP/microtubule affinity-regulating kinase 3; MAP/microtubule affinity-regulating kinase 4; MAP/microtubule affinity-regulating kinase 4L; MAP/microtubule affinity-regulating kinase like 1; MAP/microtubule affinity-regulating kinase-like 1; MARK; MARK1; mark1 {ECO:0000312; MARK2; mark2 {ECO:0000312; MARK3; MARK4; MARK4 serine/threonine protein kinase; MARK4L; MARK4S; MARKL1; MARKL1L; microtubule affinity regulating kinase 1; microtubule affinity regulating kinase 2; microtubule affinity regulating kinase 3; microtubule affinity regulating kinase 4; mKIAA1477; mPar-1c; MPK10; MPK-10; Par-1; PAR1 homolog; PAR1 homolog b; PAR1 homolog c; PAR1A; Par-1a; Par1b; Par-1b; Par1c; Par-1c; PAR-1D; protein kinase STK10; RGD:619882}; RGD:708483}; Ser/Thr protein kinase PAR-1; Ser/Thr protein kinase PAR-1B; serine/threonine kinase; serine/threonine protein kinase EMK; serine/threonine-protein kinase MARK1; Serine/threonine-protein kinase MARK2; serine/threonine-protein kinase p78; testicular tissue protein Li 117 | |
Rabbit | |
Antigen affinity chromatography | |
RUO | |
117016, 13728, 170577, 17169, 2011, 226778, 232944, 4139, 4140, 57787, 60328, 680407 | |
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. | |
Liquid |
Immunohistochemistry (Paraffin), Immunocytochemistry | |
1 mg/mL | |
PBS with 50% glycerol and 0.02% sodium azide; pH 7.2 | |
O08678, O08679, P27448, Q03141, Q05512, Q7KZI7, Q8CIP4, Q8VHF0, Q8VHJ5, Q96L34, Q9P0L2 | |
MARK1, MARK2, MARK3, MARK4 | |
Synthetic peptide corresponding to amino acids 180-230 of human MARK1. | |
100 μL | |
Primary | |
Human, Mouse, Rat | |
Antibody | |
IgG |
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