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Invitrogen™ Mast Cell Chymase Polyclonal Antibody
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Catalog No. PIPA5119025
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200 μL
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PIPA5119025 200 μL
PIPA5121781 20 μL
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Catalog No. PIPA5119025 Supplier Invitrogen™ Supplier No. PA5119025
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Rabbit Polyclonal Antibody

Mast Cell Chymase Polyclonal Antibody for Western Blot

This gene product is a chymotryptic serine proteinase that belongs to the peptidase family S1. It is expressed in mast cells and thought to function in the degradation of the extracellular matrix, the regulation of submucosal gland secretion, and the generation of vasoactive peptides. In the heart and blood vessels, this protein, rather than angiotensin converting enzyme, is largely responsible for converting angiotensin I to the vasoactive peptide angiotensin II. Angiotensin II has been implicated in blood pressure control and in the pathogenesis of hypertension, cardiac hypertrophy, and heart failure. Thus, this gene product is a target for cardiovascular disease therapies. This gene maps to 14q11. 2 in a cluster of genes encoding other proteases.
TRUSTED_SUSTAINABILITY

Specifications

Antigen Mast Cell Chymase
Applications Western Blot
Classification Polyclonal
Concentration 0.72 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.05% ProClin 300; pH 7.4
Gene CMA1
Gene Accession No. P21844, P23946
Gene Alias alpha-chymase; Chymase; chymase 1; chymase 1 preproprotein transcript E; chymase 1 preproprotein transcript I; chymase 1, mast cell; chymase, heart; chymase, mast cell; CMA1; CYH; CYM; mast cell; Mast cell chymase 1; mast cell protease 3; Mast cell protease 5; mast cell protease I; Mast cell protease III; MCP3P; Mcp5; Mcp-5; Mcpt3; Mcpt5; MCT1; mMCP-5; rMCP-3; rMCP-5; rMCP-III
Gene Symbols CMA1
Host Species Rabbit
Immunogen Recombinant protein Chymase 1, Mast Cell. The antigen corresponds to amino acid range 9-247 of the target protein.
Purification Method Protein A, Antigen affinity chromatography
Quantity 200 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 1215, 17228
Target Species Human, Mouse
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG
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