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Invitrogen™ MASTL Monoclonal Antibody (235CT7.8.2.3)
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Catalog No. PIMA518112
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400 μL
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Catalog No. Quantity
PIMA518112 400 μL
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Catalog No. PIMA518112 Supplier Invitrogen™ Supplier No. MA518112
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Description

Mouse Monoclonal Antibody

MASTL Monoclonal Antibody for Western Blot, ICC/IF

MASTL or microtubule associated serine/threonine kinase-like belongs to the MAST family, AGC Ser/Thr protein kinase group. MASTL promotes mitotic progression and cell cycle reentry after DNA damage. Loss of MASTL leads to defects in chromosome condensation, separation, and other aspects of mitotic progression, which is primarily mediated by inhibiting PP2A/B55 delta. Overexpression of MASTL is correlated with cancer progression, poor patient survival, and tumor recurrence in various cancers. Mutations at this locus have been associated with autosomal dominant thrombocytopenia, also known as thrombocytopenia-2. Alternatively spliced transcript variants have been described for this locus.
TRUSTED_SUSTAINABILITY

Specifications

Antigen MASTL
Applications Western Blot, Immunocytochemistry
Classification Monoclonal
Clone 235CT7.8.2.3
Concentration 0.5 mg/mL
Conjugate Unconjugated
Formulation PBS with 0.09% sodium azide; pH 7.4
Gene MASTL
Gene Accession No. Q96GX5
Gene Alias 2700091H24Rik; C88295; GREATWALL; greatwall kinase homolog; greatwall protein kinase; GW; GWL; hGWL; Mastl; MAST-L; microtubule associated serine/threonine kinase like; microtubule associated serine/threonine kinase-like; microtubule-associated serine/threonine-protein kinase-like; RP11-85G18.2; Serine/threonine-protein kinase greatwall; THC2
Gene Symbols MASTL
Host Species Mouse
Immunogen MASTL recombinant protein.
Purification Method Protein G
Quantity 400 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 84930
Target Species Human
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG1 κ
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