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MATH1 Rabbit anti-Human, Polyclonal, Bioss
SDP

Catalog No. 501985467
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50-198-5467 100 μL
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Catalog No. 50-198-5467 Supplier Bioss Supplier No. BS3522R
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Description

Rabbit Polyclonal Antibody

The Drosophila atonal gene produces a protein with basic helix loop helix (bHLH) domains that plays an essential role in the development of the Drosophila nervous system. Mammalian atonal homolog 1 (MATH-1) is a helix-loop-helix (HLH) transcription factor that is structurally homologous to the product of the Drosophila proneural gene atonal. MATH-1, so known as Atoh1, Ath1 or HATH-1, is a 351 amino acid protein with an atonal-related basic HLH domain. In mice, expression of MATH-1 takes place by embryonic day 9. 5 and initially localizes to the cranial ganglions and the dorsal part of the central nervous system. Prominent expression of MATH-1 is in the dorsal part of the central nervous system but becomes restricted to the external granular layer of the cerebellum by day 18 and is undetectable in the adult nervous system. It is suggested that MATH-1 may play a role in the differentiation of subsets of neural cells by activating E box-dependent transcription.

Specifications

Antigen MATH1
Applications Immunofluorescence, Immunohistochemistry (Paraffin)
Classification Polyclonal
Concentration 1 μg/mL
Conjugate Unconjugated
Formulation PBS with 1% BSA, 50% glycerol and 0.09% sodium azide; pH
Gene Atoh1
Gene Accession No. Q92858
Gene Alias Ath1; Atoh1; atonal bHLH transcription factor 1; atonal homolog 1; atonal homolog 1 (Drosophila); atonal homolog bHLH transcription factor 1; BHLHA14; BOS_6479; Class A basic helix-loop-helix protein 14; H MATH-1; hATH1; Helix-loop-helix protein hATH-1; Helix-loop-helix protein mATH-1; LOC100354967; mATH1; MATH-1; Protein atonal homolog 1; RGD1565171
Gene Symbols Atoh1
Host Species Rabbit
Immunogen KLH conjugated synthetic peptide derived from human MATH1.
Purification Method Protein A
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 474
Target Species Human
Content And Storage -20°C
Product Type Antibody
Form Liquid
Isotype IgG
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