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MATH1 Rabbit anti-Human, Polyclonal, Bioss
SDP

Rabbit Polyclonal Antibody

Supplier:  Bioss BS3522R

Encompass_Preferred

Catalog No. 50-198-5467


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Description

Description

The Drosophila atonal gene produces a protein with basic helix loop helix (bHLH) domains that plays an essential role in the development of the Drosophila nervous system. Mammalian atonal homolog 1 (MATH-1) is a helix-loop-helix (HLH) transcription factor that is structurally homologous to the product of the Drosophila proneural gene atonal. MATH-1, so known as Atoh1, Ath1 or HATH-1, is a 351 amino acid protein with an atonal-related basic HLH domain. In mice, expression of MATH-1 takes place by embryonic day 9. 5 and initially localizes to the cranial ganglions and the dorsal part of the central nervous system. Prominent expression of MATH-1 is in the dorsal part of the central nervous system but becomes restricted to the external granular layer of the cerebellum by day 18 and is undetectable in the adult nervous system. It is suggested that MATH-1 may play a role in the differentiation of subsets of neural cells by activating E box-dependent transcription.
Specifications

Specifications

MATH1
Polyclonal
Unconjugated
Atoh1
Ath1; Atoh1; atonal bHLH transcription factor 1; atonal homolog 1; atonal homolog 1 (Drosophila); atonal homolog bHLH transcription factor 1; BHLHA14; BOS_6479; Class A basic helix-loop-helix protein 14; H MATH-1; hATH1; Helix-loop-helix protein hATH-1; Helix-loop-helix protein mATH-1; LOC100354967; mATH1; MATH-1; Protein atonal homolog 1; RGD1565171
Rabbit
Protein A
RUO
474
-20°C
Liquid
Immunofluorescence, Immunohistochemistry (Paraffin)
1 μg/mL
PBS with 1% BSA, 50% glycerol and 0.09% sodium azide; pH
Q92858
Atoh1
KLH conjugated synthetic peptide derived from human MATH1.
100 μL
Primary
Human
Antibody
IgG
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