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Invitrogen™ MATN3 Polyclonal Antibody
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Catalog No. PIPA5112604
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100 μL
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PIPA5112604 100 μL
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Catalog No. PIPA5112604 Supplier Invitrogen™ Supplier No. PA5112604
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Rabbit Polyclonal Antibody

MATN3 Polyclonal Antibody for IHC (P), ELISA

Matrilins (MATNs) are a family of non-collagenous extra-cellular matrix (ECM) proteins consisting of four known members that have been proposed to play key roles in modulating cellular phenotypes during chondrogenesis of mesenchymal stem cells (MSCs). MATN1 and MATN3 are expressed specifically in cartilage and are among the most up-regulated ECM proteins during chondrogenesis. MATN3 is composed of a single N-terminal von Willebrand Factor A (vWFA) domain followed by four epidermal growth factor (EGF) repeats and a coiled-coil domain whereas MATN1 is composed of two vWFA domains separated by one EGF-like domain. MATN1 or MATN3 may play a role in modulating chondrogenesis during the chondrocyte differentiation process. Mutations of this gene have been associated with variety of inherited chondrodysplasias. Recent studies show that aberrant expression and processing of MATN3 are hallmarks of conventional cartilaginous neoplasms.
TRUSTED_SUSTAINABILITY

Specifications

Antigen MATN3
Applications ELISA, Immunohistochemistry (Paraffin)
Classification Polyclonal
Concentration 4.05 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
Gene MATN3
Gene Accession No. O15232
Gene Alias AV009181; B14.5b; CI-B14.5b; DIPOA; EDM5; HOA; Matn3; matrilin 3; matrilin-3; NADHDH2; NDUFC2; OADIP; OS2
Gene Symbols MATN3
Host Species Rabbit
Immunogen Recombinant Human Matrilin-3 protein (277-486AA).
Purification Method Antigen affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 4148
Target Species Human, Mouse
Content And Storage -20°C or -80°C if preferred
Product Type Antibody
Form Liquid
Isotype IgG
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