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Invitrogen™ MATN3 Polyclonal Antibody
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Catalog No. PIPA579635
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100 μg
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Catalog No. Quantity
PIPA579635 100 μg
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Catalog No. PIPA579635 Supplier Invitrogen™ Supplier No. PA579635
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Description

Rabbit Polyclonal Antibody

Reconstitute with 0.2 mL of distilled water to yield a concentration of 500 μg/mL. Positive Control - WB: 293T Cell, COLO320 Cell, HELA Cell, A549 Cell.

Matrilins (MATNs) are a family of non-collagenous extra-cellular matrix (ECM) proteins consisting of four known members that have been proposed to play key roles in modulating cellular phenotypes during chondrogenesis of mesenchymal stem cells (MSCs). MATN1 and MATN3 are expressed specifically in cartilage and are among the most up-regulated ECM proteins during chondrogenesis. MATN3 is composed of a single N-terminal von Willebrand Factor A (vWFA) domain followed by four epidermal growth factor (EGF) repeats and a coiled-coil domain whereas MATN1 is composed of two vWFA domains separated by one EGF-like domain. MATN1 or MATN3 may play a role in modulating chondrogenesis during the chondrocyte differentiation process. Mutations of this gene have been associated with variety of inherited chondrodysplasias. Recent studies show that aberrant expression and processing of MATN3 are hallmarks of conventional cartilaginous neoplasms.
TRUSTED_SUSTAINABILITY

Specifications

Antigen MATN3
Applications Western Blot
Classification Polyclonal
Concentration 500 μg/mL
Conjugate Unconjugated
Formulation PBS with 5mg BSA and 0.05mg sodium azide, 0.05mg thimerosal
Gene MATN3
Gene Accession No. O15232
Gene Alias AV009181; B14.5b; CI-B14.5b; DIPOA; EDM5; HOA; Matn3; matrilin 3; matrilin-3; NADHDH2; NDUFC2; OADIP; OS2
Gene Symbols MATN3
Host Species Rabbit
Immunogen A synthetic peptide corresponding to a sequence at the C-terminus of human Matrilin 3 (466-486aa NTKLDDILEKLKINEYGQIHR).
Purification Method Antigen affinity chromatography
Quantity 100 μg
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 4148
Target Species Human
Content And Storage -20°C
Product Type Antibody
Form Lyophilized
Isotype IgG
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