Invitrogen™ MB67 Monoclonal Antibody (OTI1B2)

Mouse Monoclonal Antibody

Supplier:  Invitrogen™ MA526713

Catalog No. PIMA526713

Description

MB67 Monoclonal Antibody for Western Blot, IHC (P)

This gene encodes a member of the nuclear receptor superfamily, and is a key regulator of xenobiotic and endobiotic metabolism. The protein binds to DNA as a monomer or a heterodimer with the retinoid X receptor and regulates the transcription of target genes involved in drug metabolism and bilirubin clearance, such as cytochrome P450 family members. Unlike most nuclear receptors, this transcriptional regulator is constitutively active in the absence of ligand but is regulated by both agonists and inverse agonists.

Specifications

• Antigen: MB67
• Classification: Monoclonal
• Concentration: 1 mg/mL
• Formulation: PBS with 1% BSA, 50% glycerol and 0.02% sodium azide; pH 7.3
• Gene Accession No.: Q14994
• Gene Symbols: NR1I3
• Immunogen: Human recombinant protein fragment corresponding to amino acids 1-236 of NR1I3 produced in E.coli.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG2a

• Applications: Immunohistochemistry (Paraffin), Western Blot
• Clone: OTI1B2
• Conjugate: Unconjugated
• Gene: NR1I3
• Gene Alias: AA209988; AI551208; Car; CAR1; CAR-beta; Care2; constitutive activator of retinoid response; constitutive active receptor; constitutive active response; constitutive androstane nuclear receptor variant 2; constitutive androstane nuclear receptor variant 3; constitutive androstane nuclear receptor variant 4; constitutive androstane nuclear receptor variant 5; constitutive androstane receptor; constitutive androstane receptor NR1I3; constitutive androstane receptor protein variant 1; constitutive androstane receptor protein variant 2; constitutive androstane receptor protein variant 3; constitutive androstane receptor protein variant 4; constitutive androstane receptor protein variant 5; constitutively transactivates RAREs; ESTM32; MB67; MGC150433; MGC97144; MGC97209; NR1I3; nuclear receptor; nuclear receptor constitutive active receptor; nuclear receptor subfamily 1 group I member 3; nuclear receptor subfamily 1, group I, member 3; orphan nuclear hormone receptor; orphan nuclear receptor MB67; strain Fischer nuclear receptor (CAR); Unknown (protein for MGC:137128)
• Host Species: Mouse
• Purification Method: Affinity Chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 9970
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
• Form: Liquid