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Invitrogen™ MB67 Polyclonal Antibody
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Catalog No. PIPA5102536
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PIPA5102536 100 μL
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Catalog No. PIPA5102536 Supplier Invitrogen™ Supplier No. PA5102536
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Description

Rabbit Polyclonal Antibody

Antibody detects endogenous levels of total NR1I3.

This gene encodes a member of the nuclear receptor superfamily, and is a key regulator of xenobiotic and endobiotic metabolism. The protein binds to DNA as a monomer or a heterodimer with the retinoid X receptor and regulates the transcription of target genes involved in drug metabolism and bilirubin clearance, such as cytochrome P450 family members. Unlike most nuclear receptors, this transcriptional regulator is constitutively active in the absence of ligand but is regulated by both agonists and inverse agonists.
TRUSTED_SUSTAINABILITY

Specifications

Antigen MB67
Applications Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry
Classification Polyclonal
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
Gene NR1I3
Gene Accession No. O35627, Q14994
Gene Alias AA209988; AI551208; Car; CAR1; CAR-beta; Care2; constitutive activator of retinoid response; constitutive active receptor; constitutive active response; constitutive androstane nuclear receptor variant 2; constitutive androstane nuclear receptor variant 3; constitutive androstane nuclear receptor variant 4; constitutive androstane nuclear receptor variant 5; constitutive androstane receptor; constitutive androstane receptor NR1I3; constitutive androstane receptor protein variant 1; constitutive androstane receptor protein variant 2; constitutive androstane receptor protein variant 3; constitutive androstane receptor protein variant 4; constitutive androstane receptor protein variant 5; constitutively transactivates RAREs; ESTM32; MB67; MGC150433; MGC97144; MGC97209; NR1I3; nuclear receptor; nuclear receptor constitutive active receptor; nuclear receptor subfamily 1 group I member 3; nuclear receptor subfamily 1, group I, member 3; orphan nuclear hormone receptor; orphan nuclear receptor MB67; strain Fischer nuclear receptor (CAR); Unknown (protein for MGC:137128)
Gene Symbols NR1I3
Host Species Rabbit
Immunogen A synthesized peptide derived from human NR1I3(Accession Q14994), corresponding to amino acid residues N207-Q257.
Purification Method Affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 12355, 9970
Target Species Human, Mouse
Content And Storage -20°C
Product Type Antibody
Form Liquid
Isotype IgG
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Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov
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