Invitrogen™ MBD3 Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA5120806

Catalog No. PIPA5120806

Description

Positive test controls include: Jurkat, K-562. The target is usually found in the following locations: Chromosome, Nucleus. Immunogen sequence: MERKSPSGKK FRSKPQLARY LGGSMDLSTF DFRTGKMLMS KMNKSRQRVR YDSSNQVKGK PDLNTALPVR QTASIFKQPV TKITNHPSNK VKSDPQKAVD QPRQLFWEKK LSGLNAFDIA EELVKTMDLP KGLQGVGPGC TDETLLSAIA SALHTSTMPI TGQLSAAVEK NPGVWLNTTQ PLCKAFMVTD EDIRKQEELV QQVRKRLEEA LMADMLAHVE ELARDGEAPL DKACAEDDDE EDEEEEEEEP DPDPE.

Regulator of genomic integrity and cellular response to DNA damage acting through ATR-mediated checkpoint signaling. Necessary for centrosome duplication. It functions as a molecular scaffold facilitating the interaction of PLK4 and CENPJ, two molecules involved in centriole formation.

Specifications

• Antigen: MBD3
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: MBD3
• Gene Alias: AI181826; AU019209; CpG binding domain 3; Mbd3; methyl-CpG binding domain protein 3; methyl-CpG-binding domain protein 3; Methyl-CpG-binding protein MBD3
• Host Species: Rabbit
• Purification Method: Affinity Chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 17192, 53615
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
• Form: Liquid

• Applications: ELISA, Western Blot
• Concentration: 0.8 mg/mL
• Formulation: PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
• Gene Accession No.: O95983, Q9Z2D8
• Gene Symbols: MBD3
• Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 1-255 of human MBD3 (NP_001268383.1).
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human, Mouse
• Product Type: Antibody
• Isotype: IgG