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Invitrogen™ MBL2 Polyclonal Antibody
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Catalog No. PIPA5109947
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100 μL
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PIPA5109947 100 μL
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Catalog No. PIPA5109947 Supplier Invitrogen™ Supplier No. PA5109947
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Description

Rabbit Polyclonal Antibody

Immunogen sequence: ETVTCEDAQK TCPAVIACSS PGINGFPGKD GRDGTKGEKG EPGQGLRGLQ GPPGKLGPPG NPGPSGSPGP KGQKGDPGKS PDGDSSLAAS ERKALQTEMA RIKKWLTFSL GKQVGNKFFL TNGEIMTFEK VKALCVKFQA SVATPRNAAE NGAIQNLIKE EAFLGITDEK TEGQFVDLTG NRLTYTNWNE GEPNNAGSDE DCVLLLKNGQ WNDVPCSTSH LAVCEFPI.

MBL2 is a calcium-dependent lectin involved in innate immune defense. It binds mannose, fucose and N-acetylglucosamine on different microorganisms and activates the lectin complement pathway. It also binds to late apoptotic cells, as well as to apoptotic blebs and to necrotic cells, but not to early apoptotic cells, facilitating their uptake by macrophages. MBL2 may bind DNA.
TRUSTED_SUSTAINABILITY

Specifications

Antigen MBL2
Applications ELISA, Immunohistochemistry (Paraffin), Western Blot
Classification Polyclonal
Concentration 1.21 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
Gene MBL2
Gene Accession No. P11226
Gene Alias 27 kDa mannan-binding protein monomeric subunit; Ab2-001; Ab2-011; cMBl; COLEC1; collectin; Collectin1; collectin-1; c-type lectin; HSMBPC; L-MBP; mannan-binding lectin; mannan-binding lectin C; mannan-binding protein; mannose binding lectin (C); mannose binding lectin 2; mannose binding lectin 2 (protein C); mannose binding lectin, liver (A); mannose binding lectin, liver (C); mannose-binding lectin; mannose-binding lectin (protein C) 2; mannose-binding lectin (protein C) 2, soluble; mannose-binding lectin (protein C) 2, soluble (opsonic defect); mannose-binding lectin 2, soluble (opsonic defect); mannose-binding lectin C; mannose-binding lectin precursor protein; mannose-binding lectin-C; mannose-binding protein; Mannose-binding protein C; mannose-binding protein C (liver); mbl; MBL2; MBL2D; MBL-C; MBP; MBP1; MBPC; MBP-C; MBPD; MGC116832; MGC116833; pMBP-27; RA-reactive factor P28A subunit; ra-reactive factor polysaccharide-binding component p28A; RaRF p28A; RARF/P28A; serum protein; MBL; soluble mannose-binding lectin
Gene Symbols MBL2
Host Species Rabbit
Immunogen Recombinant fusion protein containing a sequence corresponding to amino acids 21-248 of human MBL2 (NP_000233.1).
Purification Method Affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 4153
Target Species Human, Rat
Content And Storage -20°C, Avoid Freeze/Thaw Cycles
Product Type Antibody
Form Liquid
Isotype IgG
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