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Invitrogen™ MBTPS1 Monoclonal Antibody (2F10E12)
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Catalog No. FEMA550278
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100 μL
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FEMA550278 100 μL
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Catalog No. FEMA550278 Supplier Invitrogen™ Supplier No. MA550278
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Description

Mouse Monoclonal Antibody

MBTPS1 Monoclonal Antibody for Western Blot, Flow, ELISA

This gene encodes a member of the subtilisin-like proprotein convertase family, which includes proteases that process protein and peptide precursors trafficking through regulated or constitutive branches of the secretory pathway. The encoded protein undergoes an initial autocatalytic processing event in the ER to generate a heterodimer which exits the ER and sorts to the cis/medial-Golgi where a second autocatalytic event takes place and the catalytic activity is acquired. It encodes a type 1 membrane bound protease which is ubiquitously expressed and regulates cholesterol or lipid homeostasis via cleavage of substrates at non-basic residues. Mutations in this gene may be associated with lysosomal dysfunction.
TRUSTED_SUSTAINABILITY

Specifications

Antigen MBTPS1
Applications ELISA, Flow Cytometry, Western Blot
Classification Monoclonal
Clone 2F10E12
Concentration 1.25 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.03% Proclin 300; pH 7.4
Gene MBTPS1
Gene Accession No. Q14703
Gene Alias 0610038M03Rik; AV003995; endopeptidase S1P; KIAA0091; MBTPS1; membrane bound transcription factor peptidase, site 1; membrane-bound transcription factor peptidase, site 1; membrane-bound transcription factor protease, site 1; membrane-bound transcription factor site-1 protease; mKIAA0091; PCSK8; proprotein convertase subtilisin/kexin type 8; S1p; S1P endopeptidase; site-1 protease; Ski1; SKI-1; Sterol-regulated luminal protease; subtilisin kexin isozyme 1; subtilisin/kexin isozyme 1; subtilisin/kexin isozyme SKI-1; subtilisin/kexin isozyme-1; Subtilisin/kexin-isozyme 1
Gene Symbols MBTPS1
Host Species Mouse
Immunogen Recombinant Human Membrane-bound transcription factor site-1 protease protein (187-400aa).
Purification Method Protein G
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 8720
Target Species Human
Content And Storage -20°C or -80°C if preferred
Product Type Antibody
Form Liquid
Isotype IgG1
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