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Invitrogen™ MBTPS1 Polyclonal Antibody
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Catalog No. PIPA5101662
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PIPA5101662 100 μL
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Catalog No. PIPA5101662 Supplier Invitrogen™ Supplier No. PA5101662
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Description

Rabbit Polyclonal Antibody

Antibody detects endogenous levels of total MBTPS1.

This gene encodes a member of the subtilisin-like proprotein convertase family, which includes proteases that process protein and peptide precursors trafficking through regulated or constitutive branches of the secretory pathway. The encoded protein undergoes an initial autocatalytic processing event in the ER to generate a heterodimer which exits the ER and sorts to the cis/medial-Golgi where a second autocatalytic event takes place and the catalytic activity is acquired. It encodes a type 1 membrane bound protease which is ubiquitously expressed and regulates cholesterol or lipid homeostasis via cleavage of substrates at non-basic residues. Mutations in this gene may be associated with lysosomal dysfunction.
TRUSTED_SUSTAINABILITY

Specifications

Antigen MBTPS1
Applications Immunohistochemistry, Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry
Classification Polyclonal
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
Gene MBTPS1
Gene Accession No. Q14703, Q9WTZ2, Q9WTZ3
Gene Alias 0610038M03Rik; AV003995; endopeptidase S1P; KIAA0091; MBTPS1; membrane bound transcription factor peptidase, site 1; membrane-bound transcription factor peptidase, site 1; membrane-bound transcription factor protease, site 1; membrane-bound transcription factor site-1 protease; mKIAA0091; PCSK8; proprotein convertase subtilisin/kexin type 8; S1p; S1P endopeptidase; site-1 protease; Ski1; SKI-1; Sterol-regulated luminal protease; subtilisin kexin isozyme 1; subtilisin/kexin isozyme 1; subtilisin/kexin isozyme SKI-1; subtilisin/kexin isozyme-1; Subtilisin/kexin-isozyme 1
Gene Symbols MBTPS1
Host Species Rabbit
Immunogen A synthesized peptide derived from human MBTPS1(Accession Q14703), corresponding to amino acid residues V201-T251.
Purification Method Affinity Chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 56453, 8720, 89842
Target Species Human, Mouse, Rat
Content And Storage -20°C
Product Type Antibody
Form Liquid
Isotype IgG
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Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov
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