Invitrogen™ MBTPS2 Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA552155

Catalog No. PIPA552155

Description

Immunogen sequence: EVAEDSPAIG PRGLFVGDLV THLQDCPVTN VQDWNECLDT IAYEPQIGYC ISASTLQQLS FPVRAYKRLD GSTECCNNHS LTDVCFSYRN NFNKRLHTCL PARKAVEATQ VCRTNKDCKK SSSSSFCIIP SLETHTR Highest antigen sequence identity to the following orthologs: Mouse - 96%, Rat - 98%.

This gene encodes a intramembrane zinc metalloprotease, which is essential in development. This protease functions in the signal protein activation involved in sterol control of transcription and the ER stress response. Mutations in this gene have been associated with ichthyosis follicularis with atrichia and photophobia (IFAP syndrome); IFAP syndrome has been quantitatively linked to a reduction in cholesterol homeostasis and ER stress response.[provided by RefSeq, Aug 2009].

Specifications

• Antigen: MBTPS2
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: MBTPS2
• Gene Alias: 9630032G22Rik; AI662535; BRESEK; endopeptidase S2P; IFAP; keratosis follicularis spinulosa decalvans; KFSD; KFSDX; LRRGT00063; Mbtps2; membrane bound transcription factor peptidase, site 2; membrane-bound transcription factor peptidase, site 2; membrane-bound transcription factor protease, site 2; membrane-bound transcription factor site-2 protease; OLMSX; S2P; S2P endopeptidase; site-2 protease; SREBPs intramembrane protease; Sterol regulatory element-binding proteins intramembrane protease
• Host Species: Rabbit
• Purification Method: Antigen affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 51360
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid

• Applications: Immunohistochemistry (Paraffin)
• Concentration: 0.05 mg/mL
• Formulation: PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
• Gene Accession No.: O43462
• Gene Symbols: MBTPS2
• Immunogen: Recombinant protein corresponding to Human MBTPS2. Recombinant protein control fragment (Product #RP-92161).
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG