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Invitrogen™ MBTPS2 Polyclonal Antibody
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Catalog No. PIPA552155
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100 μL
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PIPA552155 100 μL
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Catalog No. PIPA552155 Supplier Invitrogen™ Supplier No. PA552155
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Description

Rabbit Polyclonal Antibody

Immunogen sequence: EVAEDSPAIG PRGLFVGDLV THLQDCPVTN VQDWNECLDT IAYEPQIGYC ISASTLQQLS FPVRAYKRLD GSTECCNNHS LTDVCFSYRN NFNKRLHTCL PARKAVEATQ VCRTNKDCKK SSSSSFCIIP SLETHTR Highest antigen sequence identity to the following orthologs: Mouse - 96%, Rat - 98%.

This gene encodes a intramembrane zinc metalloprotease, which is essential in development. This protease functions in the signal protein activation involved in sterol control of transcription and the ER stress response. Mutations in this gene have been associated with ichthyosis follicularis with atrichia and photophobia (IFAP syndrome); IFAP syndrome has been quantitatively linked to a reduction in cholesterol homeostasis and ER stress response.[provided by RefSeq, Aug 2009].
TRUSTED_SUSTAINABILITY

Specifications

Antigen MBTPS2
Applications Immunohistochemistry (Paraffin)
Classification Polyclonal
Concentration 0.05 mg/mL
Conjugate Unconjugated
Formulation PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
Gene MBTPS2
Gene Accession No. O43462
Gene Alias 9630032G22Rik; AI662535; BRESEK; endopeptidase S2P; IFAP; keratosis follicularis spinulosa decalvans; KFSD; KFSDX; LRRGT00063; Mbtps2; membrane bound transcription factor peptidase, site 2; membrane-bound transcription factor peptidase, site 2; membrane-bound transcription factor protease, site 2; membrane-bound transcription factor site-2 protease; OLMSX; S2P; S2P endopeptidase; site-2 protease; SREBPs intramembrane protease; Sterol regulatory element-binding proteins intramembrane protease
Gene Symbols MBTPS2
Host Species Rabbit
Immunogen Recombinant protein corresponding to Human MBTPS2. Recombinant protein control fragment (Product #RP-92161).
Purification Method Antigen affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 51360
Target Species Human
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG
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