MBTPS2 Rabbit anti-Human, Polyclonal, Invitrogen™

Rabbit Polyclonal Antibody

Manufacturer:  Invitrogen PA548486

Catalog No. PA548486

Description

Predicted to react with bovine and mouse based on sequence homology.

This gene encodes a intramembrane zinc metalloprotease, which is essential in development. This protease functions in the signal protein activation involved in sterol control of transcription and the ER stress response. Mutations in this gene have been associated with ichthyosis follicularis with atrichia and photophobia (IFAP syndrome); IFAP syndrome has been quantitatively linked to a reduction in cholesterol homeostasis and ER stress response.[provided by RefSeq, Aug 2009].

Specifications

• Antigen: MBTPS2
• Classification: Polyclonal
• Formulation: PBS with 0.09% sodium azide
• Gene Accession No.: O43462
• Gene Alias: Membrane-bound transcription factor site-2 protease, Endopeptidase S2P, Sterol regulatory element-binding proteins intramembrane protease, SREBPs intramembrane protease, MBTPS2, S2P
• Host Species: Rabbit
• Isotype: IgG
• Quantity: 400 μL
• Storage Requirements: -20° C, Avoid Freeze/Thaw Cycles
• Primary or Secondary: Primary
• Gene ID (Entrez): 51360

• Applications: Immunohistochemistry (Paraffin), Western Blot
• Conjugate: Unconjugated
• Gene: MBTPS2
• Format: Liquid
• Gene Symbols: MBTPS2
• Immunogen: KLH conjugated synthetic peptide between 15-44 amino acids from the N-terminal region of human MBTPS2.
• Purification Method: Antigen affinity chromatography
• Regulatory Status: RUO
• Type: Antibody
• Monoclonal or Polyclonal: Polyclonal
• Target Species: Human