MC-1R/MC1 Receptor Rabbit anti-Human, Polyclonal, Bioss

Catalog No.	Quantity
50-198-3219	100 μL

Catalog No. 50-198-3219 Supplier Bioss Supplier No. BS1419R

Description

Rabbit Polyclonal Antibody

MC1R, a Melanocortin Receptor, mediates the effects of melanocyte-stimulating hormone (MSH) and adrenocorticotropic hormone (ACTH). MSH and its receptor, MC1R, are key regulators of melanogenesis. They control the relative proportions of red pheomelanin and black photoprotective eumelanin in the skin by increasing the production of eumelanin. Non-functional, truncated forms of the receptor lead to lighter coat color in animals. In contrast, constitutively active receptors lead to darker color.

Specifications

• Antigen: MC-1R/MC1 Receptor
• Applications: Flow Cytometry, Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot
• Classification: Polyclonal
• Concentration: 1 μg/mL
• Conjugate: Unconjugated
• Formulation: PBS with 1% BSA, 50% glycerol and 0.09% sodium azide; pH
• Gene: Mc1r
• Gene Accession No.: Q01726
• Gene Alias: alpha melanocyte stimulating hormone receptor; CMM5; e; extension recessive yellow; MC1 receptor; MC1R; MC1-R; melanocortin 1 receptor; melanocortin 1 receptor (alpha melanocyte stimulating hormone receptor); Melanocortin receptor 1; melanocortin-1 receptor; Melanocyte-stimulating hormone receptor; melanotropin receptor; MSHR; Msh-r; Mshra; SHEP2; Tob; tobacco darkening
• Gene Symbols: Mc1r
• Host Species: Rabbit
• Immunogen: KLH conjugated synthetic peptide derived from mouse MC-1R .
• Purification Method: Protein A
• Quantity: 100 μL
• Regulatory Status: RUO
• Primary or Secondary: Primary
• Gene ID (Entrez): 4157
• Target Species: Human
• Content And Storage: -20°C
• Product Type: Antibody
• Form: Liquid
• Isotype: IgG