MC-1R/MC1 Receptor Rabbit anti-Human, Polyclonal, Bioss 

Rabbit Polyclonal Antibody

Manufacturer:  Bioss BS1419R

Catalog No. 50-198-3219

Description

MC1R, a Melanocortin Receptor, mediates the effects of melanocyte-stimulating hormone (MSH) and adrenocorticotropic hormone (ACTH). MSH and its receptor, MC1R, are key regulators of melanogenesis. They control the relative proportions of red pheomelanin and black photoprotective eumelanin in the skin by increasing the production of eumelanin. Non-functional, truncated forms of the receptor lead to lighter coat color in animals. In contrast, constitutively active receptors lead to darker color.

Specifications

• Antigen: MC-1R/MC1 Receptor
• Applications: Flow Cytometry, Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot
• Conjugate: Unconjugated
• Gene: Mc1r
• Format: Liquid
• Host Species: Rabbit
• Isotype: IgG
• Quantity: 100 μL
• Storage Requirements: -20°C
• Primary or Secondary: Primary
• Gene ID (Entrez): 4157

• Gene Symbol: Mc1r
• Concentration: 1 μg/mL
• Formulation: PBS with 1% BSA, 50% glycerol and 0.09% sodium azide; pH
• Gene Accession No.: Q01726
• Gene Alias: alpha melanocyte stimulating hormone receptor; CMM5; e; extension recessive yellow; MC1 receptor; MC1R; MC1-R; melanocortin 1 receptor; melanocortin 1 receptor (alpha melanocyte stimulating hormone receptor); Melanocortin receptor 1; melanocortin-1 receptor; Melanocyte-stimulating hormone receptor; melanotropin receptor; MSHR; Msh-r; Mshra; SHEP2; Tob; tobacco darkening
• Immunogen: KLH conjugated synthetic peptide derived from mouse MC-1R .
• Purification Method: Protein A
• Regulatory Status: RUO
• Type: Antibody
• Monoclonal or Polyclonal: Polyclonal
• Target Species: Human