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Invitrogen™ MC1R Recombinant Rabbit Monoclonal Antibody (6D1S5)
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Catalog No. PIMA535136
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100 μL
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PIMA535136 100 μL
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Catalog No. PIMA535136 Supplier Invitrogen™ Supplier No. MA535136
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Description

Rabbit Recombinant Monoclonal Antibody

Immunogen sequence: MAVQGSQRRL LGSLNSTPTA IPQLGLAANQ TGARCLEVSI SDGLFLSLGL VSLVENALVV ATIAKNRNLH SPMYCFICCL ALSDLLVSGS NVLETAVILL.

MC1R, a Melanocortin Receptor, mediates the effects of melanocyte-stimulating hormone (MSH) and adrenocorticotropic hormone (ACTH). MSH and its receptor, MC1R, are key regulators of melanogenesis. They control the relative proportions of red pheomelanin and black photoprotective eumelanin in the skin by increasing the production of eumelanin. Non-functional, truncated forms of the receptor lead to lighter coat color in animals. In contrast, constitutively active receptors lead to darker color.
TRUSTED_SUSTAINABILITY

Specifications

Antigen MC1R
Applications ELISA, Western Blot
Classification Recombinant Monoclonal
Clone 6D1S5
Concentration 0.95 mg/mL
Conjugate Unconjugated
Formulation PBS with 0.05% BSA, 50% glycerol and 0.02% sodium azide; pH 7.3
Gene Mc1r
Gene Accession No. Q01726, Q01727
Gene Alias alpha melanocyte stimulating hormone receptor; CMM5; e; extension recessive yellow; MC1 receptor; MC1R; MC1-R; melanocortin 1 receptor; melanocortin 1 receptor (alpha melanocyte stimulating hormone receptor); melanocortin receptor 1; melanocortin-1 receptor; melanocyte-stimulating hormone receptor; melanotropin receptor; MSHR; MSH-R; Mshra; SHEP2; Tob; tobacco darkening
Gene Symbols Mc1r
Host Species Rabbit
Immunogen A synthetic peptide corresponding to a sequence within amino acids 1-100 of human MC1 Receptor (Q01726).
Purification Method Affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 102552838, 17199, 4157
Target Species Human, Mouse, Rat
Content And Storage -20°C, Avoid Freeze/Thaw Cycles
Product Type Antibody
Form Liquid
Isotype IgG
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