Invitrogen™ MC1R Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA575342

Catalog No. PIPA575342

Description

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

MC1R, a Melanocortin Receptor, mediates the effects of melanocyte-stimulating hormone (MSH) and adrenocorticotropic hormone (ACTH). MSH and its receptor, MC1R, are key regulators of melanogenesis. They control the relative proportions of red pheomelanin and black photoprotective eumelanin in the skin by increasing the production of eumelanin. Non-functional, truncated forms of the receptor lead to lighter coat color in animals. In contrast, constitutively active receptors lead to darker color.

Specifications

• Antigen: MC1R
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: Mc1r
• Gene Alias: alpha melanocyte stimulating hormone receptor; CMM5; e; extension recessive yellow; MC1 receptor; MC1R; MC1-R; melanocortin 1 receptor; melanocortin 1 receptor (alpha melanocyte stimulating hormone receptor); melanocortin receptor 1; melanocortin-1 receptor; melanocyte-stimulating hormone receptor; melanotropin receptor; MSHR; MSH-R; Mshra; SHEP2; Tob; tobacco darkening
• Host Species: Rabbit
• Purification Method: Antigen Affinity Chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 102552838, 17199, 4157
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid

• Applications: Western Blot, Immunocytochemistry
• Concentration: 1 mg/mL
• Formulation: PBS with 50% glycerol and 0.02% sodium azide; pH 7.2
• Gene Accession No.: Q01726, Q01727
• Gene Symbols: Mc1r
• Immunogen: Synthetic peptide corresponding to amino acids 271-317 of Human MC1-R.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human, Mouse, Rat
• Product Type: Antibody
• Isotype: IgG