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MC1R Polyclonal Antibody, Invitrogen™

Catalog No. PIPA123524
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25 μg
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Catalog No. Quantity
PIPA123524 25 μg
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Catalog No. PIPA123524 Supplier Thermo Scientific Supplier No. PA123524

Description

Rabbit Polyclonal Antibody

PA1-23524 detects melanocortin 1 receptor in human samples.

MC1R, a Melanocortin Receptor, mediates the effects of melanocyte-stimulating hormone (MSH) and adrenocorticotropic hormone (ACTH). MSH and its receptor, MC1R, are key regulators of melanogenesis. They control the relative proportions of red pheomelanin and black photoprotective eumelanin in the skin by increasing the production of eumelanin. Non-functional, truncated forms of the receptor lead to lighter coat color in animals. In contrast, constitutively active receptors lead to darker color.
TRUSTED_SUSTAINABILITY

Specifications

Antigen MC1R
Applications Immunohistochemistry (Paraffin)
Classification Polyclonal
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with 0.1% sodium azide
Gene Mc1r
Gene Accession No. Q01726
Gene Alias alpha melanocyte stimulating hormone receptor; CMM5; e; extension recessive yellow; MC1 receptor; MC1R; MC1-R; melanocortin 1 receptor; melanocortin 1 receptor (alpha melanocyte stimulating hormone receptor); melanocortin receptor 1; melanocortin-1 receptor; melanocyte-stimulating hormone receptor; melanotropin receptor; MSHR; MSH-R; Mshra; SHEP2; Tob; tobacco darkening
Gene Symbols Mc1r
Host Species Rabbit
Immunogen Synthetic peptide, conjugated to KLH, corresponding to the 3rd cytoplasmic domain of human Melanocortin 1 Receptor.
Purification Method Antigen affinity chromatography
Quantity 25 μg
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 4157
Target Species Human
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG
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Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov
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