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MCAM/CD146 Antibody (MUC18/1130), PE/Cy7, Novus Biologicals™
SDP

Catalog No. N247777PEC7 Shop All R&D Systems Products
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Catalog No. N247777PEC7 Supplier Novus Biologicals Supplier No. NBP247777PECY7
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Description

Mouse Monoclonal Antibody

MCAM/CD146 Monoclonal specifically detects MCAM/CD146 in Human samples. It is validated for Flow Cytometry.

Specifications

Antigen MCAM/CD146
Applications Flow Cytometry
Classification Monoclonal
Clone MUC18/1130
Conjugate PE-Cyanine7
Dilution Flow Cytometry
Formulation PBS with 0.05% Sodium Azide
Gene Alias CD146, CD146 antigen, cell surface glycoprotein MUC18, Cell surface glycoprotein P1H12, melanoma adhesion molecule, melanoma cell adhesion moleculeS-endo 1 endothelial-associated antigen, Melanoma-associated antigen A32, Melanoma-associated antigen MUC18, MUC18Gicerin
Gene Symbols MCAM
Host Species Mouse
Immunogen Recombinant full-length human MCAM/CD146 protein (Uniprot: P43121)
Purification Method Protein A or G purified
Quantity 0.1 mL
Research Discipline Cancer, Mesenchymal Stem Cell Markers, Phospho Specific, Stem Cell Markers
Primary or Secondary Primary
Gene ID (Entrez) 4162.0
Test Specificity The human Mel-CAM gene maps to chromosome 11q23 and encodes a trans-membrane glycoprotein, also designated MCAM, MUC 18 or CD146, that belongs to the immunoglobulin superfamily and functions as a Ca2+-independent cell adhesion molecule. Mel-CAM expression is restricted to advanced primary and metastatic melanomas and to cell lines of the neuroectodermal lineage, but not normal melanocytes. Mel-CAM is found on 80% of advanced primary human melanomas and correlates well with development of metastatic disease.
Target Species Human
Content And Storage Store at 4°C in the dark. Do not freeze.
Isotype IgG1 κ
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