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Invitrogen™ MCF2 Polyclonal Antibody
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Catalog No. PIPA588796
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100 μL
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PIPA588796 100 μL
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Catalog No. PIPA588796 Supplier Invitrogen™ Supplier No. PA588796
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Description

Rabbit Polyclonal Antibody

Immunogen sequence: VKMTWLKEIR NILLKQQELL TVKKRKQQDQ LTERDKFQIS LQQNDEKQQG AFISTEETEL EHTSTVVEVC EAIASVQAEA NTVWTEASQS AEISEEPAEW SSNYFYPTYD ENEEENRPLM RPVSEMALLY; Positive Samples: HT-29; Cellular Location: Cytoplasm, Membrane.

Guanine nucleotide exchange factor (GEF) that modulates the Rho family of GTPases. Promotes the conversion of some member of the Rho family GTPase from the GDP-bound to the GTP-bound form. Isoform 1 exhibits no activity toward RHOA, RAC1 or CDC42. Isoform 2 exhibits decreased GEF activity toward CDC42. Isoform 3 exhibits a weak but significant activity toward RAC1 and CDC42. Isoform 4 exhibits significant activity toward RHOA and CDC42. The truncated DBL oncogene is active toward RHOA, RAC1 and CDC42.
TRUSTED_SUSTAINABILITY

Specifications

Antigen MCF2
Applications ELISA, Western Blot
Classification Polyclonal
Concentration 0.22 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.01% thimerosal; pH 7.3
Gene MCF2
Gene Accession No. P10911
Gene Alias ARHGEF21; B230117G22Rik; DBL; DBL-transforming protein; MCF.2 cell line derived transforming sequence; mcf.2 transforming sequence; MCF2; Mcf-2; MCF2-transforming protein; Oncogene MCF2 (oncogene DBL); OTTHUMP00000024159; proto-oncogene DBL; Proto-oncogene MCF-2; RGD1566098
Gene Symbols MCF2
Host Species Rabbit
Immunogen Recombinant fusion protein containing a sequence corresponding to amino acids 872-1001 of human MCF2 (NP_0011653471).
Purification Method Affinity Chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 109904, 4168
Target Species Human, Mouse
Content And Storage -20°C, Avoid Freeze/Thaw Cycles
Product Type Antibody
Form Liquid
Isotype IgG
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