Invitrogen™ MCFD2 Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA575704

Catalog No. PIPA575704

Description

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Multiple coagulation factor deficiency protein 2 (MCFD2) is localized in the endoplasmic reticulum-Golgi intermediate compartment (ERGIC) through a direct, calcium-dependent interaction with LMAN1. The MCFD2-LMAN1 complex forms a specific cargo receptor for the transport of selected proteins from the endoplasmic reticulum to the Golgi apparatus. Mutations in the MCFD2 gene may cause of factor V and factor VIII combined deficiency (F5F8D). F5F8D is an autosomal recessive human bleeding disorder characterized by the reduction of both clotting proteins.

Specifications

• Antigen: MCFD2
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: Mcfd2
• Gene Alias: 1810021C21Rik; F5F8D; F5F8D2; LMAN1IP; MCFD2; multiple coagulation factor deficiency 2; multiple coagulation factor deficiency protein 2; Multiple coagulation factor deficiency protein 2 homolog; neural stem cell derived neuronal survival protein; neural stem cell-derived neuronal survival protein; Sdnsf; stem cell derived neuronal survival protein
• Host Species: Rabbit
• Purification Method: Antigen affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 246117, 90411
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid

• Applications: Western Blot
• Concentration: 1 mg/mL
• Formulation: PBS with 50% glycerol and 0.02% sodium azide; pH 7.2
• Gene Accession No.: Q8K5B3, Q8NI22
• Gene Symbols: Mcfd2
• Immunogen: Synthetic peptide corresponding to residues in Human MCFD2.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human, Rat
• Product Type: Antibody
• Isotype: IgG