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Invitrogen™ MCHR2 Polyclonal Antibody
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Catalog No. PIPA575329
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100 μL
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PIPA575329 100 μL
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Catalog No. PIPA575329 Supplier Invitrogen™ Supplier No. PA575329
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Description

Rabbit Polyclonal Antibody

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Melanin-concentrating hormone (MCH) is a 19 amino acid cyclic neuropeptide which is mainly expressed in the hypothalamus. MCH modulates feeding behavior, aggression, anxiety, arousal and reproductive function in mammals by controlling the release of luteinizing hormone (LH). The melanin-concentrating hormone receptor (MCHR, also designated SLC-1) is a glycosylated G-protein coupled receptor that migrates between 45-50 kDa on SDS-PAGE. MCHR mediates the effects of MCH through Gai and/or Gaq signaling and is expressed in several regions of the brain, including the cerebral cortex, amygdala, thalamus and hypothalamus. MCH and MCHR have also been implicated in stimulating leptin expression and secretion in adipocytes, which suggests that the melanin-concentrating hormone and its receptor may be potential targets for modulating obesity.
TRUSTED_SUSTAINABILITY

Specifications

Antigen MCHR2
Applications Immunohistochemistry (Paraffin), Immunocytochemistry
Classification Polyclonal
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.02% sodium azide; pH 7.2
Gene MCHR2
Gene Accession No. Q969V1
Gene Alias G protein-coupled receptor 145; G protein-coupled receptor slt; GPR145; G-protein coupled receptor 145; GPRv17; MCH receptor 2; MCH2; Mch2 receptor; MCH2R; MCH-2R; MCHR2; MCH-R2; MCHR-2; melanin concentrating hormone receptor 2; melanin-concentrating hormone 2; melanin-concentrating hormone receptor 2; SLT; SLT receptor
Gene Symbols MCHR2
Host Species Rabbit
Immunogen Synthetic peptide corresponding to amino acids 300-340 of Human MCH-2R.
Purification Method Antigen affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 84539
Target Species Human, Mouse, Rat
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG
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