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Invitrogen™ MCHR2 Polyclonal Antibody
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Catalog No. PIPA131050
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25 μg
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Catalog No. Quantity
PIPA131050 25 μg
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Catalog No. PIPA131050 Supplier Invitrogen™ Supplier No. PA131050
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Description

Rabbit Polyclonal Antibody

PA1-31050 detects GPCR MCH2 from human samples.

Melanin-concentrating hormone (MCH) is a 19 amino acid cyclic neuropeptide which is mainly expressed in the hypothalamus. MCH modulates feeding behavior, aggression, anxiety, arousal and reproductive function in mammals by controlling the release of luteinizing hormone (LH). The melanin-concentrating hormone receptor (MCHR, also designated SLC-1) is a glycosylated G-protein coupled receptor that migrates between 45-50 kDa on SDS-PAGE. MCHR mediates the effects of MCH through Gai and/or Gaq signaling and is expressed in several regions of the brain, including the cerebral cortex, amygdala, thalamus and hypothalamus. MCH and MCHR have also been implicated in stimulating leptin expression and secretion in adipocytes, which suggests that the melanin-concentrating hormone and its receptor may be potential targets for modulating obesity.
TRUSTED_SUSTAINABILITY

Specifications

Antigen MCHR2
Applications Immunohistochemistry (Paraffin), Immunocytochemistry
Classification Polyclonal
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with 0.1% sodium azide
Gene MCHR2
Gene Accession No. Q969V1
Gene Alias G protein-coupled receptor 145; G protein-coupled receptor slt; GPR145; G-protein coupled receptor 145; GPRv17; MCH receptor 2; MCH2; Mch2 receptor; MCH2R; MCH-2R; MCHR2; MCH-R2; MCHR-2; melanin concentrating hormone receptor 2; melanin-concentrating hormone 2; melanin-concentrating hormone receptor 2; SLT; SLT receptor
Gene Symbols MCHR2
Host Species Rabbit
Immunogen Synthetic 19 amino acid peptide from C-terminus of human MCHR2.
Purification Method Antigen affinity chromatography
Quantity 25 μg
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 84539
Target Species Human
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG
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