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Invitrogen™ MCM2 Polyclonal Antibody
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Catalog No. PIPA587986
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100 μL
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PIPA587986 100 μL
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Catalog No. PIPA587986 Supplier Invitrogen™ Supplier No. PA587986
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Description

Rabbit Polyclonal Antibody

Immunogen sequence: PFEVNMEETI YQNYQRIRIQ ESPGKVAAGR LPRSKDAILL ADLVDSCKPG DEIELTGIYH NNYDGSLNTA NGFPVFATVI LANHVAKKDN KVAVGELTDE DVKMITSLSK DQQIGEKIFA SIAPSIYGHE DIKRGLALAL FGGEPKNPGG KHKVRGDINV LLCGDPGTAK SQFLKYIEKV SSRAIFTTGQ GASAVGLTAY VQRHPVSREW TLEAGALVLA DRGVCLIDEF DKMNDQDRTS IHEAMEQQSI SISKAGIVTS LQARCTVIAA ANPIGGRYDP SLTFSENVDL TEPIISRFDI LCVVRDTVDP VQDEMLARFV VGSHVRHHPS NKEEEGLANG S; Positive Samples: SW480, SH-SY5Y, Raji, A-549, HeLa, HL-60, Mouse thymus; Cellular Location: Nucleus.

MCM2 (Mini chromosome maintenance protein 2) is involved in regulating DNA replication. MCM2 (also called CDCL1, mitotin and BM28), is a human nuclear protein that is crucial in the cell cycle, being involved in the onset of DNA replication and cell division. It is similar to members of the family of early S-phase proteins. MCM2 has been mapped to 3q21. From its localization, CDCL1 became a candidate for an oncogene affected by chromosomal breaks in acute myeloid leukemia (AML).
TRUSTED_SUSTAINABILITY

Specifications

Antigen MCM2
Applications ELISA, Western Blot
Classification Polyclonal
Concentration 0.2 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
Gene MCM2
Gene Accession No. P49736, P97310
Gene Alias AA959861; AW476101; BM28; CCNL1; cdc19; CDCL1; cell devision cycle-like 1; cyclin-like 1; D3S3194; DFNA70; DNA replication licensing factor MCM2; Kiaa0030; MCM DNA helicase complex subunit MCM2; Mcm2; Mcmd2; MGC10606; mini chromosome maintenance deficient 2; minichromosome maintenance complex component 2; minichromosome maintenance deficient 2 (mitotin); minichromosome maintenance deficient 2 mitotin; minichromosome maintenance deficient 2 mitotin (S. cerevisiae); Minichromosome maintenance protein 2; Minichromosome maintenance protein 2 homolog; MITOTIN; mKIAA0030; Nuclear protein BM28; YBL023C; YBL0438
Gene Symbols MCM2
Host Species Rabbit
Immunogen Recombinant fusion protein containing a sequence corresponding to amino acids 360-700 of human MCM2 (NP_0045172).
Purification Method Affinity Chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 17216, 4171
Target Species Human, Mouse, Rat
Content And Storage -20°C, Avoid Freeze/Thaw Cycles
Product Type Antibody
Form Liquid
Isotype IgG
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