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Invitrogen™ MCM3 Recombinant Rabbit Monoclonal Antibody (9Z5W4)
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Catalog No. PIMA535115
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PIMA535115 100 μL
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Catalog No. PIMA535115 Supplier Invitrogen™ Supplier No. MA535115
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Description

Rabbit Recombinant Monoclonal Antibody

Immunogen sequence: MAGTVVLDDV ELREAQRDYL DFLDDEEDQG IYQSKVRELI SDNQYRLIVN VNDLRRKNEK RANRLLNNAF EELVAFQRAL KDFVASIDAT YAKQYEEFYV.

The protein encoded by this gene is one of the highly conserved mini-chromosome maintenance proteins (MCM) that are involved in the initiation of eukaryotic genome replication. The hexameric protein complex formed by MCM proteins is a key component of the pre-replication complex (pre_RC) and may be involved in the formation of replication forks and in the recruitment of other DNA replication related proteins. This protein is a subunit of the protein complex that consists of MCM2-7. It has been shown to interact directly with MCM5/CDC46. This protein also interacts with, and thus is acetlyated by MCM3AP, a chromatin-associated acetyltransferase. The acetylation of this protein inhibits the initiation of DNA replication and cell cycle progression.
TRUSTED_SUSTAINABILITY

Specifications

Antigen MCM3
Applications ELISA, Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot, Immunocytochemistry
Classification Recombinant Monoclonal
Clone 9Z5W4
Concentration 0.4 mg/mL
Conjugate Unconjugated
Formulation PBS with 0.05% BSA, 50% glycerol and 0.02% sodium azide; pH 7.3
Gene MCM3
Gene Accession No. P25205, P25206
Gene Alias AL033361; C80350; cervical cancer proto-oncogene 5; DNA polymerase alpha holoenzyme-associated protein P1; DNA replication factor MCM3; DNA replication licensing factor MCM3; HCC5; hRlf beta subunit; MCM3; MCM3 minichromosome maintenance deficient 3; Mcmd; Mcmd3; MGC1157; mini chromosome maintenance deficient; minichromosome maintenance complex component 3; minichromosome maintenance deficient 3; minichromosome maintenance deficient 3 (S. cerevisiae); P1; P1.h; p1.m; p102; P1-MCM3; replication licensing factor, beta subunit; RLF subunit beta; RLFB; RP1-108C2.3
Gene Symbols MCM3
Host Species Rabbit
Immunogen A synthetic peptide corresponding to a sequence within amino acids 1-100 of human MCM3 (P25205).
Purification Method Affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 17215, 316273, 4172
Target Species Human, Mouse, Rat
Content And Storage -20°C, Avoid Freeze/Thaw Cycles
Product Type Antibody
Form Liquid
Isotype IgG
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