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Invitrogen™ MCM3 Polyclonal Antibody
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Catalog No. PIPA552104
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100 μL
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PIPA552104 100 μL
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Catalog No. PIPA552104 Supplier Invitrogen™ Supplier No. PA552104
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Description

Rabbit Polyclonal Antibody

Immunogen sequence: KMVSAAFMKK YIHVAKIIKP VLTQESATYI AEEYSRLRSQ DSMSSDTART SPVTARTLET LIRLATAHAK ARMSKTVDLQ DAEEAVELVQ YAYFKKVLEK EKKRKKRSED ESETEDEEEK SQEDQEQKRK RRKTR Highest antigen sequence identity to the following orthologs: Mouse - 95%, Rat - 93%.

The protein encoded by this gene is one of the highly conserved mini-chromosome maintenance proteins (MCM) that are involved in the initiation of eukaryotic genome replication. The hexameric protein complex formed by MCM proteins is a key component of the pre-replication complex (pre_RC) and may be involved in the formation of replication forks and in the recruitment of other DNA replication related proteins. This protein is a subunit of the protein complex that consists of MCM2-7. It has been shown to interact directly with MCM5/CDC46. This protein also interacts with, and thus is acetlyated by MCM3AP, a chromatin-associated acetyltransferase. The acetylation of this protein inhibits the initiation of DNA replication and cell cycle progression.
TRUSTED_SUSTAINABILITY

Specifications

Antigen MCM3
Applications Immunohistochemistry (Paraffin), Western Blot
Classification Polyclonal
Concentration 0.1 mg/mL
Conjugate Unconjugated
Formulation PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
Gene MCM3
Gene Accession No. P25205, P25206
Gene Alias AL033361; C80350; cervical cancer proto-oncogene 5; DNA polymerase alpha holoenzyme-associated protein P1; DNA replication factor MCM3; DNA replication licensing factor MCM3; HCC5; hRlf beta subunit; MCM3; MCM3 minichromosome maintenance deficient 3; Mcmd; Mcmd3; MGC1157; mini chromosome maintenance deficient; minichromosome maintenance complex component 3; minichromosome maintenance deficient 3; minichromosome maintenance deficient 3 (S. cerevisiae); P1; P1.h; p1.m; p102; P1-MCM3; replication licensing factor, beta subunit; RLF subunit beta; RLFB; RP1-108C2.3
Gene Symbols MCM3
Host Species Rabbit
Immunogen Recombinant protein corresponding to Human MCM3. Recombinant protein control fragment (Product #RP-102497).
Purification Method Antigen affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 17215, 316273, 4172
Target Species Human, Mouse, Rat
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG
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