Invitrogen™ MCM5 Monoclonal Antibody (CRCT5.1)

Mouse Monoclonal Antibody

Supplier:  Invitrogen™ MA180807

Catalog No. MA180807

Description

Heat-mediated antigen retrieval using a sodium citrate buffer (pH 6.0) is recommended for the staining of paraffin sections. A suggested positive control for immunohistochemical applications is tonsil or cervical carcinoma. Mouse anti Human Mcm5 antibody, clone CRCT5.1 recognizes human Mcm-5 (minichromosome maintenance protein 5), also known as DNA replication licensing factor MCM5 or P1-CDC46.

The protein encoded by this gene is structurally very similar to the CDC46 protein from S. cerevisiae, a protein involved in the initiation of DNA replication. The encoded protein is a member of the MCM family of chromatin-binding proteins and can interact with at least two other members of this family. The encoded protein is upregulated in the transition from the G0 to G1/S phase of the cell cycle and may actively participate in cell cycle regulation.

Specifications

• Antigen: MCM5
• Classification: Monoclonal
• Concentration: 1 mg/mL
• Formulation: PBS with 0.09% sodium azide; pH 7.4
• Gene Accession No.: P33992
• Gene Symbols: MCM5
• Immunogen: Bacterially expressed human MCM5.
• Quantity: 100 μg
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG2b

• Applications: Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry
• Clone: CRCT5.1
• Conjugate: Unconjugated
• Gene: MCM5
• Gene Alias: AA617332; AI324988; AL033333; Cdc46; CDC46 homolog; DNA replication licensing factor MCM5; MCM5; MCM5 minichromosome maintenance deficient 5, cell division cycle 46; Mcmd5; MGC5315; minichromosome maintenance complex component 5; minichromosome maintenance deficient 5 (cell division cycle 46); minichromosome maintenance deficient 5, cell division cycle 46; minichromosome maintenance deficient 5, cell division cycle 46 (S. cerevisiae); P1-CDC46
• Host Species: Mouse
• Purification Method: Protein A
• Regulatory Status: RUO
• Gene ID (Entrez): 4174
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid

Safety and Handling

WARNING: Reproductive Harm - www.P65Warnings.ca.gov