Invitrogen™ MCM5 Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA5120925

Catalog No. PIPA5120925

Description

Positive test controls include: HeLa, Jurkat, SW620, Mouse spleen, Rat thymus. The target is usually found in the following locations: Nucleus. Immunogen sequence: MSGFDDPGIF YSDSFGGDAQ ADEGQARKSQ LQRRFKEFLR QYRVGTDRTG FTFKYRDELK RHYNLGEYWI EVEMEDLASF DEDLADYLYK QPAEHLQLLE EAAKEVADEV TRPRPSGEEV LQDIQVMLKS DASPSSIRSL KSDMMSHLVK IPGIIIAASA VRAKATRISI QCRSCRNTLT NIAMRPGLEG YALPRKCNTD QAGRPKCPLD PYFIMPDKCK CVDFQTLKLQ.

The protein encoded by this gene is structurally very similar to the CDC46 protein from S. cerevisiae, a protein involved in the initiation of DNA replication. The encoded protein is a member of the MCM family of chromatin-binding proteins and can interact with at least two other members of this family. The encoded protein is upregulated in the transition from the G0 to G1/S phase of the cell cycle and may actively participate in cell cycle regulation.

Specifications

• Antigen: MCM5
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: MCM5
• Gene Alias: AA617332; AI324988; AL033333; Cdc46; CDC46 homolog; DNA replication licensing factor MCM5; MCM5; MCM5 minichromosome maintenance deficient 5, cell division cycle 46; Mcmd5; MGC5315; minichromosome maintenance complex component 5; minichromosome maintenance deficient 5 (cell division cycle 46); minichromosome maintenance deficient 5, cell division cycle 46; minichromosome maintenance deficient 5, cell division cycle 46 (S. cerevisiae); P1-CDC46
• Host Species: Rabbit
• Purification Method: Affinity Chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 17218, 291885, 4174
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
• Form: Liquid

• Applications: ELISA, Immunoprecipitation, Western Blot, Immunocytochemistry
• Concentration: 0.15 mg/mL
• Formulation: PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
• Gene Accession No.: P33992, P49718
• Gene Symbols: MCM5
• Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 1-230 of human MCM5 (NP_006730.2).
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human, Mouse, Rat
• Product Type: Antibody
• Isotype: IgG